Recombinant Human Sodium/Hydrogen Exchanger 1 / NHE-1 protein (ab152688)

Overview

  • Product name
    Recombinant Human Sodium/Hydrogen Exchanger 1 / NHE-1 protein
  • Protein length
    Protein fragment

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      36 kDa including tags
    • Amino acids
      31 to 130

Specifications

Our Abpromise guarantee covers the use of ab152688 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    SDS-PAGE

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 ug/ul.
    Best use within three months from the date of receipt of this protein.

    Previously labelled as Sodium / Hydrogen Exchanger 1.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • amiloride-sensitive
    • APNH
    • APNH1
    • FLJ42224
    • Na Li countertransporter
    • Na(+)/H(+) antiporter
    • Na(+)/H(+) exchanger 1
    • Na+ H+ antiporter
    • Na+ H+ antiporter amiloride-sensitive
    • Na+ H+ exchanger 1
    • NHE-1
    • NHE1
    • OTTHUMP00000004468
    • SL9A1_HUMAN
    • SLC9A1
    • Sodium / Hydrogen Exchanger 1
    • Sodium hydrogen exchanger 1
    • Sodium/hydrogen exchanger 1
    • solute carrier family 9
    • Solute carrier family 9 member 1
    • Solute carrier family 9 sodium hydrogen exchanger isoform 1 antiporter Na+ H+ amiloride sensitive
    • Solute carrier family 9 subfamily A (NHE1 cation proton antiporter 1) member 1
    • Solute carrier family 9 subfamily A member 1
    see all
  • Function
    Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
  • Tissue specificity
    Kidney and intestine.
  • Sequence similarities
    Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
    O-glycosylated.
  • Cellular localization
    Membrane.
  • Information by UniProt

Images

  • 12.5% SDS-PAGE showing ab152688 stained with Coomassie Blue.

References

ab152688 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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