Description

  • Product name

    Recombinant Human SOSTDC1 protein (denatured)
    See all SOSTDC1 proteins and peptides
  • Purity

    > 85 % SDS-PAGE.

  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSFKNDATE ILYSHVVKPV PAHPSSNSTL NQARNGGRHF SNTGLDRNTR VQVGCRELRS TKYISDGQCT SISPLKELVC AGECLPLPVL PNWIGGGYGT KYWSRRSSQE WRCVNDKTRT QRIQLQCQDG STRTYKITVV TACKCKRYTR QHNESSHNFE SMSPAKPVQH HRERKRASKS SKHSMS
    • Predicted molecular weight

      23 kDa including tags
    • Amino acids

      24 to 206
    • Tags

      His tag N-Terminus
  • Description

    Recombinant Human SOSTDC1 protein

Specifications

Our Abpromise guarantee covers the use of ab139616 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 2.4% Urea, 0.32% Tris HCl, 10% Glycerol

General Info

  • Alternative names

    • CDA019
    • DKFZp564D206
    • Ectodermal BMP inhibitor
    • Ectodin
    • sclerostin domain containing 1
    • Sclerostin domain containing protein 1
    • Sclerostin domain-containing protein 1
    • SOSD1_HUMAN
    • Sostdc1
    • USAG-1
    • USAG1
    • Uterine sensitization associated gene 1 protein
    • Uterine sensitization-associated gene 1 protein
    • Wise
    see all
  • Function

    May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling (By similarity). Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner.
  • Tissue specificity

    Highly expressed in kidney and weakly in lung.
  • Sequence similarities

    Belongs to the sclerostin family.
    Contains 1 CTCK (C-terminal cystine knot-like) domain.
  • Cellular localization

    Secreted.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab139616 (3µg).

References

ab139616 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab139616.
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