Product nameRecombinant human SPHK2 protein
See all SPHK2 proteins and peptides
Protein lengthFull length protein
SourceBaculovirus infected Sf9 cells
Amino Acid Sequence
Molecular weight110 kDa including tags
Amino acids1 to 654
Our Abpromise guarantee covers the use of ab125634 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activityThe specific activity of ab125634 was determined to be 30 nmol/min/mg.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol, 0.88% Sodium chloride
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- SK 2
- Sphingosine kinase 2
- Sphingosine kinase type 2
FunctionCatalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra-and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides.
Sequence similaritiesContains 1 DAGKc domain.
Cellular localizationCytoplasm. Membrane and Lysosome membrane.
- Information by UniProt
ab125634 has not yet been referenced specifically in any publications.