Description

  • Product name

    Recombinant Human SSX2 protein (denatured)
    See all SSX2 proteins and peptides
  • Purity

    > 85 % SDS-PAGE.

  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH RSMNGDDAFA RRPTVGAQIP EKIQKAFDDI AKYFSKEEWE KMKASEKIFY VYMKRKYEAM TKLGFKATLP PFMCNKRAED FQGNDLDNDP NRGNQVERPQ MTFGRLQGIS PKIMPKKPAE EGNDSEEVPE ASGPQNDGKE LCPPGKPTTS EKIHERSGPK RGEHAWTHRL RERKQLVIYE EISDPEEDDE
    • Predicted molecular weight

      22 kDa
    • Amino acids

      1 to 188
    • Tags

      His tag N-Terminus
  • Description

    Recombinant Human SSX2 protein

Specifications

Our Abpromise guarantee covers the use of ab181904 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.0
    Constituents: 0.32% Tris HCl, 10% Glycerol, 2.4% Urea

General Info

  • Alternative names

    • Cancer/testis antigen 5.2
    • Cancer/testis antigen family 5, member 2a
    • Cancer/testis antigen family 5, member 2b
    • CT5.2
    • CT5.2A
    • CT5.2b
    • HD21
    • hom mel 40
    • HOM-MEL-40
    • MGC119055
    • MGC15364
    • MGC3884
    • Protein SSX2
    • RP11-552J9.2
    • sarcoma, synovial, X-chromosome related 2
    • SSx
    • SSX2
    • SSX2-SYT fusion gene, included
    • SSX2_HUMAN
    • SSX2B
    • Synovial sarcoma
    • synovial sarcoma X breakpoint 2
    • Synovial sarcoma, X breakpoint 2B
    • Tumor antigen HOM-MEL-40
    • X breakpoint 2
    see all
  • Function

    Could act as a modulator of transcription.
  • Tissue specificity

    Expressed at high level in the testis. Expressed at low level in thyroid. Not detected in tonsil, colon, lung, spleen, prostate, kidney, striated and smooth muscles. Detected in rhabdomyosarcoma and fibrosarcoma cell lines. Not detected in mesenchymal and epithelial cell lines.
  • Involvement in disease

    Note=A chromosomal aberration involving SSX2 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency).
  • Sequence similarities

    Belongs to the SSX family.
    Contains 1 KRAB-related domain.
  • Cellular localization

    Nucleus.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of 3ug ab181904 stained with Coomassie Blue.

References

ab181904 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab181904.
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