Recombinant Human ST3GAL2 protein (ab159509)

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Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MKCSLRVWFLSVAFLLVFIMSLLFTYSHHSMATLPYLDSGALDGTHRVKL VPGYAGLQRLSKERLSGKSCACRRCMGDAGASDWFDSHFDGNISPVWTRE NMDLPPDVQRWWMMLQPQFKSHNTNEVLEKLFQIVPGENPYRFRDPHQCR RCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFM YPESAKNLPANVSFVLVPFKVLDLLWIASALSTGQIRFTYAPVKSFLRVD KEKVQIYNPAFFKYIHDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGFG ADSRGNWHHYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKIEVYRGN
    • Amino acids
      1 to 350
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab159509 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • 3-GalNAc-alpha-2
    • 3-sialyltransferase
    • 3-sialyltransferase 2
    • 3-ST 2
    • Alpha 2
    • Alpha 2,3-ST
    • Beta-galactoside alpha-2
    • Beta-galactoside alpha-2,3-sialyltransferase
    • CMP N-acetylneuraminate beta galactosamide alpha 2,3 sialyltransferase
    • CMP-N-acetylneuraminate-beta-galactosamide-alpha-2
    • Gal NAc6S
    • Gal-beta-1
    • Gal-NAc6S
    • SIA4B_HUMAN
    • Sialyltransferase 4B
    • sialyltransferase 4B (beta-galactosidase alpha-2,3-sialytransferase)
    • SIAT4-B
    • SIAT4B
    • ST3 beta-galactoside alpha-2,3-sialyltransferase 2
    • ST3Gal II
    • ST3GAL2
    • ST3GalA.2
    • ST3GalII
    see all
  • Function
    It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found in terminal carbohydrate groups of certain glycoproteins, oligosaccharides and glycolipids. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values.
  • Tissue specificity
    Highly expressed in skeletal muscle and heart and to a much lesser extent in brain, placenta, liver and pancreas. Scarcely detectable in lung and kidney.
  • Pathway
    Protein modification; protein glycosylation.
  • Sequence similarities
    Belongs to the glycosyltransferase 29 family.
  • Post-translational
    modifications
    The soluble form derives from the membrane form by proteolytic processing.
  • Cellular localization
    Golgi apparatus > Golgi stack membrane. Secreted. Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
  • Information by UniProt

Images

  • ab159509 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab159509 has not yet been referenced specifically in any publications.

Publishing research using ab159509? Please let us know so that we can cite the reference in this datasheet.

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