Recombinant Human ST6GALNAC6 protein (ab162320)

Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      GYVPILGNKTLPSRCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPT TGYSADVGNKTTYRVVAHSSVFRVLRRPQEFVNRTPETVFIF
    • Amino acids
      91 to 182
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab162320 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • 6-sialyltransferase 6
    • 6-sialyltransferase VI
    • Alpha N acetylgalactosaminide alpha 2 6 sialyltransferase 6
    • Alpha-N-acetylgalactosaminide alpha-2
    • CMP NeuAC:(beta) N acetylgalactosaminide (alpha)2 6 sialyltransferase member VI
    • GalNAc alpha 2 6 sialyltransferase VI
    • GalNAc alpha-2
    • hST6GalNAc VI
    • RP11 203J24.3
    • SIA7F_HUMAN
    • Sialyltransferase 7F
    • Sialyltransferase7F
    • Sialytransferase 7 ((alpha N acetylneuraminyl 2 3 betagalactosyl 1 3) N acetyl galactosaminide alpha 2 6 sialytransferase) F
    • SIAT 7F
    • SIAT7-F
    • SIAT7F
    • ST6 (alpha N acetyl neuraminyl 2 3 beta galactosyl 1 3) N acetylgalactosaminide alpha 2 6 sialyltransferase 6
    • ST6GalNAc VI
    • ST6GALNAC6
    • ST6GalNAcVI
    see all
  • Function
    Alpha-2,6-sialyltransferase involved in the synthesis of alpha-series gangliosides. Has activity toward GD1a, GT1b and GM1b. Has no activity toward glycoproteins. Responsible for the biosynthesis of DSGG (disialylgalactosylgloboside) from MSGG (monosialylgalactosylgloboside) in normal and malignant kidney. Participates in the synthesis of disialyl Lewis a (Le(a)).
  • Tissue specificity
    Expressed in kidney, in proximal tubule epithelial cells. Expressed in colon cell lines.
  • Sequence similarities
    Belongs to the glycosyltransferase 29 family.
  • Cellular localization
    Golgi apparatus membrane.
  • Information by UniProt

Images

  • ab162320 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab162320 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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