Description

  • Product name

    Recombinant Human STK38 protein
    See all STK38 proteins and peptides
  • Purity

    > 80 % Densitometry.
    The purity was determined to be >80% by densitometry
  • Expression system

    Baculovirus
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Predicted molecular weight

      81 kDa including tags
    • Amino acids

      2 to 465

Specifications

Our Abpromise guarantee covers the use of ab101505 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.307% Glutathione, 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol, 0.87% Sodium chloride

General Info

  • Alternative names

    • NDR
    • NDR 1
    • Ndr Ser/Thr kinase-like protein
    • NDR1
    • NDR1 protein kinase
    • Nuclear Dbf2 related kinase 1
    • nuclear Dbf2-related 1
    • Nuclear Dbf2-related kinase 1
    • Nuclear Dbf2-related protein
    • Serine/threonine protein kinase 38
    • Serine/threonine-protein kinase 38
    • STK 38
    • STK38
    • STK38_HUMAN
    see all
  • Function

    Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its nonphosphorylated form and inhibits autophosphorylation of MAP3K2.
  • Tissue specificity

    Ubiquitously expressed with highest levels observed in peripheral blood leukocytes.
  • Sequence similarities

    Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications

    ISGylated.
  • Cellular localization

    Nucleus. Cytoplasm.
  • Information by UniProt

Images

  • SDS-PAGE analysis of ab101505.

References

This product has been referenced in:

  • Klimek C  et al. The Hippo network kinase STK38 contributes to protein homeostasis by inhibiting BAG3-mediated autophagy. Biochim Biophys Acta Mol Cell Res 1866:1556-1566 (2019). Read more (PubMed: 31326538) »
See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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