Key features and details
- Expression system: Escherichia coli
- Active: Yes
- Suitable for: WB, Functional Studies
Product nameRecombinant human Sumo 3 protein
See all Sumo 3 proteins and peptides
Biological activityThe final fraction of enzyme contains a single polypeptide band of 11 kDa.
Expression systemEscherichia coli
Protein lengthFull length protein
Predicted molecular weight11 kDa
Our Abpromise guarantee covers the use of ab3802 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesThe final fraction of enzyme contains a single polypeptide band of 11 kDa.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.68% Imidazole
Constituents: 0.0087% PMSF, 0.0154% DTT, 0.158% Tris HCl, 10% Glycerol, 0.58% Sodium chloride
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- Small ubiquitin like modifier 3
- Small ubiquitin related modifier 3
- Small ubiquitin-related modifier 3
FunctionUbiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4.
Tissue specificityExpressed predominantly in liver.
Sequence similaritiesBelongs to the ubiquitin family. SUMO subfamily.
Contains 1 ubiquitin-like domain.
modificationsPolymeric chains can be formed through Lys-11 cross-linking.
Cleavage of precursor form by SENP1, SENP2 or SENP5 is necessary for function.
- Information by UniProt
Left Lane: Topo I protein (Topo I fragment: ab3828)
Note: Topo I is S35-Met labeled.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab3802 has not yet been referenced specifically in any publications.