Description

  • Product name

    Recombinant Human Surfactant protein D/SP-D (denatured)
    See all Surfactant protein D/SP-D proteins and peptides
  • Purity

    > 80 % SDS-PAGE.

  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      VASLRQQ VEALQGQVQH LQAAFSQYKK VELFPNGQSV GEKIFKTAGF VKPFTEAQLL CTQAGGQLAS PRSAAENAAL QQLVVAKNEA AFLSMTDSKT EGKFTYPTGE SLVYSNWAPG EPNDDGGSED CVEIFTNGKW NDRACGEKRL VVCEF
    • Predicted molecular weight

      19 kDa including tags
    • Amino acids

      224 to 375
    • Tags

      His tag N-Terminus
    • Additional sequence information

      NP_003010

Specifications

Our Abpromise guarantee covers the use of ab181961 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Additional notes

    Previously labelled as Surfactant protein D.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.0
    Constituents: 0.32% Tris HCl, 10% Glycerol, 2.4% Urea

General Info

  • Alternative names

    • COLEC 7
    • COLEC7
    • Collectin-7
    • Collectin7
    • Lung surfactant protein D
    • PSP D
    • PSP-D
    • PSP-D Surfactant protein D
    • PSPD
    • Pulmonary surfactant apoprotein
    • Pulmonary surfactant associated protein D
    • Pulmonary surfactant associated protein PSP-D
    • Pulmonary surfactant-associated protein D
    • SFTP 4
    • SFTP4
    • SFTPD
    • SFTPD_HUMAN
    • SP D
    • SP-D
    • Surfactant associated protein pulmonary 4
    • Surfactant protein D
    • Surfactant pulmonary associated protein D
    see all
  • Function

    Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
  • Sequence similarities

    Belongs to the SFTPD family.
    Contains 1 C-type lectin domain.
    Contains 1 collagen-like domain.
  • Post-translational
    modifications

    The N-terminus is blocked.
    Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates.
  • Cellular localization

    Secreted > extracellular space > extracellular matrix. Secreted > extracellular space > surface film.
  • Information by UniProt

Images

  •  15% SDS-PAGE gel analysis of ab18961 (3 µg)

References

ab181961 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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