The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
ATP dependent RNA helicase SUPV3L1, mitochondrial
ATP-dependent RNA helicase SUPV3L1
S. Cerevisiae suppressor of var 1 3 like 1
suppressor of var1 (S.cerevisiae) 3 like 1
Suppressor of var1 3 like 1
Suppressor of var1 3 like 1 (S. cerevisiae)
Suppressor of var1 3 like 1 (S. cerevisiae)(SUV3)
Suppressor of var1 3 like protein 1
Suppressor of var1 3-like protein 1
SUPV 3 L 1
SUV 3 L 1
SUV3 like protein 1
SUV3-like protein 1
Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.
Belongs to the helicase family. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain.