Recombinant Human SV2A protein (ab153025)

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SDS-PAGE - Recombinant Human SV2A protein (ab153025)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: ELISA, WB

    Description

    • Product name

      Recombinant Human SV2A protein
      See all SV2A proteins and peptides

    • Expression system

      Wheat germ

    • Protein length

      Protein fragment

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        HLQAVDYASRTKVFPGERVGHVTFNFTLENQIHRGGQYFNDKFIGLRLKS VSFEDSL

      • Amino acids

        474 to 530

      • Tags

        GST tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab153025 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      ELISA

      Western blot

    • Form

      Liquid

    • Additional notes

       

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    General Info

    • Alternative names

      • KIAA0736
      • OTTHUMP00000014065
      • SV2
      • Sv2a
      • SV2A_HUMAN
      • Synaptic vesicle glycoprotein 2
      • Synaptic vesicle glycoprotein 2A
      • Synaptic vesicle protein 2a
      see all

    • Function

      Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.

    • Sequence similarities

      Belongs to the major facilitator superfamily.

    • Post-translational
      modifications

      Phosphorylation by CK1 of the N-terminal cytoplasmic domain regulates interaction with SYT1.
      N-glycosylated.

    • Cellular localization

      Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Enriched in chromaffin granules, not present in adrenal microsomes. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human SV2A protein (ab153025)
      SDS-PAGE - Recombinant Human SV2A protein (ab153025)
      ab153025 on a 12.5% SDS-PAGE stained with Coomassie Blue.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab153025? Please let us know so that we can cite the reference in this datasheet.

    ab153025 has not yet been referenced specifically in any publications.

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