Recombinant Human Synaptotagmin V protein (ab171492)

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Description

  • Product name

    Recombinant Human Synaptotagmin V protein
    See all Synaptotagmin V proteins and peptides

  • Purity

    > 90 % SDS-PAGE.
    ab171492 was purified using conventional chromatography techniques.

  • Expression system

    Escherichia coli

  • Accession

    O00445

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSLGRLQYS LDYDFQSGQL LVGILQAMGL AALDLGGSSD PYVRVYLLPD KRRRYETKVH RQTLNPHFGE TFAFKVPYVE LGGRVLVMAV YDFDRFSRND AIGEVRVPMS SVDLGRPVQA WRELQAAPRE EQEKLGDICF SLRYVPTAGK LTVIVLEAKN LKKMDVGGLS DPYVKVHLLQ GGKKVRKKKT TIKKNTLNPY YNEAFSFEVP CDQVQKVQVE LTVLDYDKLG KNEAIGRVAV GAAAGGAGLR HWADMLANPR RPIAQWHSLR PPDRVRLLPA P

    • Predicted molecular weight

      34 kDa including tags

    • Amino acids

      109 to 386

    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab171492 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.03% DTT, 0.32% Tris HCl, 40% Glycerol, 1.17% Sodium chloride

General Info

  • Alternative names

    • Synaptotagmin 5
    • Synaptotagmin IX
    • Synaptotagmin V
    • Synaptotagmin-5
    • Syt5
    • SYT5_HUMAN
    • SytV
    see all

  • Function

    May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface.

  • Sequence similarities

    Belongs to the synaptotagmin family.
    Contains 2 C2 domains.

  • Cellular localization

    Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Recycling endosome membrane. In mast cells, localizes to the endocytic recycling compartment.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human Synaptotagmin V protein (ab171492)
    SDS-PAGE - Recombinant Human Synaptotagmin V protein (ab171492)
    15% SDS-PAGE analysis of 3µg ab171492.

References

ab171492 has not yet been referenced specifically in any publications.

Publishing research using ab171492? Please let us know so that we can cite the reference in this datasheet.

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