Recombinant Human Syntaxin 8 protein (ab185399)

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Description

  • Product name

    Recombinant Human Syntaxin 8 protein

  • Purity

    > 95 % SDS-PAGE.
    Purity determined also by determined by SEC-HPLC. Lyophilized from a 0.2 µM filtered solution

  • Endotoxin level

    > 1.000 Eu/µg

  • Expression system

    Escherichia coli

  • Accession

    Q9UNK0

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MAPDPWFSTYDSTCQIAQEIAEKIQQRNQYERKGEKAPKLTVTIRALLQN LKEKIALLKDLLLRA VSTHQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSSLMSEE AKRGAPNPWLFEEPE ETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQN EIIDDLANLVENTDE KLRNETRRVNMVDRKSASCG

    • Predicted molecular weight

      25 kDa

    • Amino acids

      1 to 215

    • Additional sequence information

      Cytoplasmic domain.

Specifications

Our Abpromise guarantee covers the use of ab185399 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    HPLC

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at Room Temperature. The lyophilized protein is stable for a few weeks at room temperature. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.4
    Constituent: 100% PBS

  • Reconstitution
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 3X PBS. Please aliquot the reconstituted solution. Aliquots of reconstituted samples are stable at < -20°C for 5 months.

General Info

  • Alternative names

    • CARB
    • STX 8
    • Stx8
    • STX8_HUMAN
    • Syntaxin-8
    • Syntaxin8
    see all

  • Function

    Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER.

  • Tissue specificity

    Highly expressed in heart. Also found in brain, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas.

  • Sequence similarities

    Belongs to the syntaxin family.
    Contains 1 t-SNARE coiled-coil homology domain.

  • Post-translational
    modifications

    Ubiquitinated by HECTD3.

  • Cellular localization

    Membrane. Preferentially associated with the early endosome. To lesser extends, also present in late endosome, the plasma membrane and coated pits.
  • Information by UniProt

References

ab185399 has not yet been referenced specifically in any publications.

Publishing research using ab185399? Please let us know so that we can cite the reference in this datasheet.

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