Recombinant Human Syntaxin 8 protein (ab185399)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Endotoxin level: > 1.000 Eu/µg
- Suitable for: SDS-PAGE, HPLC
Description
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Product name
Recombinant Human Syntaxin 8 protein -
Purity
> 95 % SDS-PAGE.
Purity determined also by determined by SEC-HPLC. Lyophilized from a 0.2 µM filtered solution -
Endotoxin level
> 1.000 Eu/µg -
Expression system
Escherichia coli -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MAPDPWFSTYDSTCQIAQEIAEKIQQRNQYERKGEKAPKLTVTIRALLQN LKEKIALLKDLLLRA VSTHQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSSLMSEE AKRGAPNPWLFEEPE ETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQN EIIDDLANLVENTDE KLRNETRRVNMVDRKSASCG -
Predicted molecular weight
25 kDa -
Amino acids
1 to 215 -
Additional sequence information
Cytoplasmic domain.
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Specifications
Our Abpromise guarantee covers the use of ab185399 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
HPLC
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituent: 100% PBS -
ReconstitutionAlways centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 3X PBS. Please aliquot the reconstituted solution. Aliquots of reconstituted samples are stable at < -20°C for 5 months.
General Info
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Alternative names
- CARB
- STX 8
- Stx8
see all -
Function
Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER. -
Tissue specificity
Highly expressed in heart. Also found in brain, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas. -
Sequence similarities
Belongs to the syntaxin family.
Contains 1 t-SNARE coiled-coil homology domain. -
Post-translational
modificationsUbiquitinated by HECTD3. -
Cellular localization
Membrane. Preferentially associated with the early endosome. To lesser extends, also present in late endosome, the plasma membrane and coated pits. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab185399 has not yet been referenced specifically in any publications.