Recombinant Human TAB3 protein (ab166083)

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SDS-PAGE - Recombinant Human TAB3 protein (ab166083)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: ELISA, WB

    Description

    • Product name

      Recombinant Human TAB3 protein

    • Expression system

      Wheat germ

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        MAQSSPQLDIQVLHDLRQRFPEIPEGVVSQCMLQNNNNLEACCRALSQES SKYLYMEYHSPDDNRMNRNRLLHINLGIHSPSSYHPGDGAQLNGGRTLVH SSSDGHIDPQHAAGKQLICLVQEPHSAPAVVAATPNYNPFFMNEQNRSAA TPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVS QNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPW QSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQC PSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAY LPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPRNQHSLY TATTPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPN PTTVFKITVGRATTENLLNLVDQEERSAAPEPIQPISVIPGSGGEKGSHK YQRSSSSGSDDYAYTQALLLHQRARMERLAKQLKLEKEELERLKSEVNGM EHDLMQRRLRRVSCTTAIPTPEEMTRLRSMNRQLQINVDCTLKEVDLLQS RGNFDPKAMNNFYDNIEPGPVVPPKPSKKDSSDPCTIERKARRISVTSKV QADIHDTQAAAADEHRTGSTQSPRTQPRDEDYEGAPWNCDSCTFLNHPAL NRCEQCEMPRYT

      • Amino acids

        1 to 712

      • Tags

        GST tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab166083 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      ELISA

      Western blot

    • Form

      Liquid

    • Additional notes

       

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    General Info

    • Alternative names

      • MAP3K7IP 3
      • Mitogen-activated protein kinase kinase kinase 7-interacting protein 3
      • NAP1
      • NF-kappa-B-activating protein 1
      • NFkB activating protein 1
      • TAB-3
      • Tab3
      • TAB3_HUMAN
      • TAK1 binding protein 3
      • TAK1-binding protein 3
      • TGF-beta-activated kinase 1 and MAP3K7-binding protein 3
      • TGF-beta-activated kinase 1-binding protein 3
      see all

    • Function

      Adapter linking MAP3K7/TAK1 and TRAF6 or TRAF2. Mediator of MAP3K7 activation, respectively in the IL1 and TNF signaling pathways. Plays a role in activation of NF-kappa-B and AP1 transcription factor. Isoform 2 may be an oncogenic factor.

    • Tissue specificity

      Widely expressed. Constitutively overexpressed in certain tumor tissues. Isoform 1 is a major transcript while isoform 2 is a minor transcript.

    • Sequence similarities

      Contains 1 CUE domain.
      Contains 1 RanBP2-type zinc finger.

    • Post-translational
      modifications

      Ubiquitinated; following IL1 stimulation or TRAF6 overexpression.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human TAB3 protein (ab166083)
      SDS-PAGE - Recombinant Human TAB3 protein (ab166083)
      ab166083 on a 12.5% SDS-PAGE stained with Coomassie Blue.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab166083? Please let us know so that we can cite the reference in this datasheet.

    ab166083 has not yet been referenced specifically in any publications.

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