Recombinant Human TAB3 protein (ab166083)

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Description

  • Product name

    Recombinant Human TAB3 protein

  • Expression system

    Wheat germ

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MAQSSPQLDIQVLHDLRQRFPEIPEGVVSQCMLQNNNNLEACCRALSQES SKYLYMEYHSPDDNRMNRNRLLHINLGIHSPSSYHPGDGAQLNGGRTLVH SSSDGHIDPQHAAGKQLICLVQEPHSAPAVVAATPNYNPFFMNEQNRSAA TPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVS QNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPW QSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQC PSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAY LPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPRNQHSLY TATTPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPN PTTVFKITVGRATTENLLNLVDQEERSAAPEPIQPISVIPGSGGEKGSHK YQRSSSSGSDDYAYTQALLLHQRARMERLAKQLKLEKEELERLKSEVNGM EHDLMQRRLRRVSCTTAIPTPEEMTRLRSMNRQLQINVDCTLKEVDLLQS RGNFDPKAMNNFYDNIEPGPVVPPKPSKKDSSDPCTIERKARRISVTSKV QADIHDTQAAAADEHRTGSTQSPRTQPRDEDYEGAPWNCDSCTFLNHPAL NRCEQCEMPRYT

    • Amino acids

      1 to 712

    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab166083 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid

  • Additional notes

     

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • MAP3K7IP 3
    • Mitogen-activated protein kinase kinase kinase 7-interacting protein 3
    • NAP1
    • NF-kappa-B-activating protein 1
    • NFkB activating protein 1
    • TAB-3
    • Tab3
    • TAB3_HUMAN
    • TAK1 binding protein 3
    • TAK1-binding protein 3
    • TGF-beta-activated kinase 1 and MAP3K7-binding protein 3
    • TGF-beta-activated kinase 1-binding protein 3
    see all

  • Function

    Adapter linking MAP3K7/TAK1 and TRAF6 or TRAF2. Mediator of MAP3K7 activation, respectively in the IL1 and TNF signaling pathways. Plays a role in activation of NF-kappa-B and AP1 transcription factor. Isoform 2 may be an oncogenic factor.

  • Tissue specificity

    Widely expressed. Constitutively overexpressed in certain tumor tissues. Isoform 1 is a major transcript while isoform 2 is a minor transcript.

  • Sequence similarities

    Contains 1 CUE domain.
    Contains 1 RanBP2-type zinc finger.

  • Post-translational
    modifications

    Ubiquitinated; following IL1 stimulation or TRAF6 overexpression.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human TAB3 protein (ab166083)
    SDS-PAGE - Recombinant Human TAB3 protein (ab166083)
    ab166083 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab166083 has not yet been referenced specifically in any publications.

Publishing research using ab166083? Please let us know so that we can cite the reference in this datasheet.

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