Description

  • Product name

    Recombinant human TAK1 + TAB1 protein
  • Biological activity

    The Specific activity of ab89692 was determined to be 10 nmol/min/mg.
  • Expression system

    Baculovirus infected Sf9 cells
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human

Specifications

Our Abpromise guarantee covers the use of ab89692 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

    Functional Studies

  • Form

    Liquid
  • Additional notes

    ab64311 (Myelin Basic Protein protein) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.0038% EGTA, 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol, 0.87% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names

    • 2310012M03Rik
    • 3' Tab1
    • B430101B05
    • C87327
    • MAP3K7
    • MAP3K7IP1
    • MEKK7
    • MGC57664
    • Mitogen activated protein kinase kinase kinase 7
    • Mitogen activated protein kinase kinase kinase 7 interacting protein 1
    • Mitogen-activated protein kinase kinase kinase 7-interacting protein 1
    • RP23-447J12.1
    • TAB1
    • TAB1_HUMAN
    • TAK1 binding protein 1
    • TAK1-binding protein 1
    • TGF beta activated kinase 1
    • TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
    • TGF-beta-activated kinase 1-binding protein 1
    • TGF1a
    • Transforming growth factor beta activated kinase 1
    • Transforming growth factor beta activated kinase binding protein 1
    see all
  • Function

    May be an important signaling intermediate between TGFB receptors and MAP3K7/TAK1. May play an important role in mammalian embryogenesis.
  • Tissue specificity

    Ubiquitous.
  • Sequence similarities

    Contains 1 PP2C-like domain.
  • Post-translational
    modifications

    Monoubiquitinated. Deubiquitinated by Y.enterocolitica YopP.
  • Information by UniProt

Images

  • The specific activity of TAK1 + TAB1 (ab89692) was determined to be 12 nmol/min/mg as per activity assay protocol
  • SDS PAGE analysis of ab89692
  • SDS PAGE analysis of ab89692
  • SDS-PAGE showing ab89692 at approximately 74kDa.
  • Kinase Assay demonstrating specific activity of ab89692.

References

ab89692 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab89692.
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