Description

  • Product name

    Recombinant human TAOK1 protein
  • Biological activity

    Specific activity: 1670 nmol/min/mg.
  • Expression system

    Baculovirus infected Sf9 cells
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Amino acids

      1 to 314

Associated products

Specifications

Our Abpromise guarantee covers the use of ab63169 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

  • Form

    Liquid
  • Additional notes

    ab64311 (Myelin Basic Protein protein) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.0038% EGTA, 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol, 0.87% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names

    • 2810468K05Rik
    • AU020252
    • D130018F14Rik
    • EC 2.7.11.1
    • FLJ14314
    • hKFC B
    • hKFC-B
    • KIAA1361
    • Kinase from chicken homolog B
    • MAP3K16
    • MARK kinase
    • MARKK
    • MGC29021
    • Microtubule affinity regulating kinase kinase
    • mKIAA1361
    • Prostate-derived sterile 20-like kinase 2
    • PSK2
    • Serine/threonine kinase TAO1
    • Serine/threonine protein kinase TAO1
    • Serine/threonine protein kinase TAO1 homolog
    • Serine/threonine-protein kinase TAO1
    • STE20 like kinase
    • STE20 like kinase PSK2
    • STE20-like kinase PSK2
    • TAO kinase 1
    • Taok1
    • TAOK1_HUMAN
    • Thousand and one amino acid protein 1
    see all
  • Function

    Phosphorylates MKK3 (By similarity). Activates the p38 MAP kinase pathway through the specific activation of the upstream MKK3 kinase.
  • Tissue specificity

    Highly expressed in the testis, and to a lower extent also expressed in brain, placenta, colon and skeletal muscle.
  • Sequence similarities

    Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications

    Autophosphorylated.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt

Images

  • The specific activity of TAOK1 (ab63169) was determined to be 28 nmol/min/mg as per activity assay protocol and was equivalent to 1630 nmol/min/mg as per radiometric assay
  • SDS PAGE analysis of ab63169
  • Sample Kinase Activity Plot.
  • ab63169 on SDS-PAGE. Molecular Weight: ~63 kDa.

References

ab63169 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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