Overview

Description

  • Nature

    Recombinant
  • Source

    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MNLLPNIESPVTRQEKMATVWDEAEQDGIGEEVLKMSTEEIIQRTRLLDS EIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVD PNDQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDL VGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVE AIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLK LAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEK AGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDR KIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVC VEAGMIALRRGATELTHEDYMEGILEVQAKKKANLQYYA
    • Molecular weight

      76 kDa including tags
    • Amino acids

      1 to 439

Associated products

Specifications

Our Abpromise guarantee covers the use of ab132642 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

    SDS-PAGE

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml. Best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • 26S protease regulatory subunit 6A
    • 26S proteasome AAA-ATPase subunit RPT5
    • Human immunodeficiency virus tat transactivator binding protein 1
    • MGC8487
    • Proteasome (prosome macropain) 26S subunit ATPase 3
    • Proteasome 26S ATPase subunit 3
    • Proteasome 26S subunit ATPase 3
    • Proteasome subunit P50
    • PRS6A_HUMAN
    • PSMC 3
    • PSMC3
    • Tat binding protein 1
    • TAT-binding protein 1
    • TBP-1
    • TBP1
    see all
  • Function

    The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity). In case of HIV-1 infection, suppresses Tat-mediated transactivation.
  • Sequence similarities

    Belongs to the AAA ATPase family.
  • Post-translational
    modifications

    Sumoylated by UBE2I in response to MEKK1-mediated stimuli.
  • Cellular localization

    Cytoplasm. Nucleus.
  • Information by UniProt

Images

  • 12.5% SDS-PAGE analysis of ab132642 stained with Coomassie Blue.

References

ab132642 has not yet been referenced specifically in any publications.

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