Product nameRecombinant Human TCEA1 protein
See all TCEA1 proteins and peptides
Purity> 90 % SDS-PAGE.
refolded and chromatographically purified.
Expression systemEscherichia coli
Protein lengthFull length protein
SequenceMASMTGGQQMGRGHHHHHHENLYFQGEDEVVRFAKKMDKMVQKKNAAGAL DLLKELKNIPMTLELLQSTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKK LLDGPSTEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETNARDT YVSSFPRAPSTSDSVRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEA IYQEIRNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTA EEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQ VQTRSADEPMTTFVVCNECGNRWKFC
Predicted molecular weight37 kDa including tags
Amino acids2 to 301
Additional sequence informationFull length protein without initiator methionine with a small T7-His-TEV cleavage site Tag (29aa) fusion at its N-terminal.
- Anti-TEV Tag antibody [KT88] (ab179875)
- Anti-6X His tag® antibody [HIS.H8] (ab18184)
- Anti-TCEA1 antibody [EPR15036] (ab184158)
- Anti-TCEA1 antibody [EPR14820(B)] (ab184181)
- Anti-TCEA1 antibody [EPR14821] (ab185947)
- Anti-6X His tag® antibody [4D11] (ab5000)
- Anti-6X His tag® antibody (ab9108)
- Anti-T7 tag® antibody (ab9115)
- Anti-T7 tag® antibody (ab9138)
Our Abpromise guarantee covers the use of ab204205 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -80°C. Avoid freeze / thaw cycle.
Constituent: 0.32% Tris HCl
Contains NaCl, KCl, EDTA, arginine, DTT and glycerol
FunctionNecessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
Involvement in diseaseNote=A chromosomal aberration involving TCEA1 may be a cause of salivary gland pleiomorphic adenomas (PA) . Pleiomorphic adenomas are the most common benign epithelial tumors of the salivary gland. Translocation t(3;8)(p21;q12) with PLAG1.
Sequence similaritiesBelongs to the TFS-II family.
Contains 1 TFIIS central domain.
Contains 1 TFIIS N-terminal domain.
Contains 1 TFIIS-type zinc finger.
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab204205 has not yet been referenced specifically in any publications.