Description

  • Product name

    Recombinant human TCPTP protein
  • Biological activity

    Specific Activity: 10 U/ug. One unit will hydrolyze 1 nmol p-nitrophenyl phosphate per minute at pH 7.4 and 30 C. Assay buffer: 50 mM HEPES, pH 7.4, 2 mM EDTA, 3mM DTT, 100 mM NaCl, 50 mM pNPP.
  • Purity

    > 95 % SDS-PAGE.

  • Expression system

    Escherichia coli
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Amino acids

      2 to 315

Specifications

Our Abpromise guarantee covers the use of ab42575 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Inhibition Assay

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.307% Glutathione, 0.0154% DTT, 0.395% Tris HCl, 0.05% Tween, 0.0584% EDTA, 50% Glycerol, 0.435% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names

    • Protein tyrosine phosphatase non receptor type 2
    • PTN2
    • PTN2_HUMAN
    • PTPN 2
    • Ptpn2
    • PTPT
    • T cell protein tyrosine phosphatase
    • T-cell protein-tyrosine phosphatase
    • TC PTP
    • TCELLPTP
    • TCPTP
    • Tyrosine protein phosphatase non receptor type 2
    • Tyrosine-protein phosphatase non-receptor type 2
    see all
  • Tissue specificity

    Isoform PTPA is probably the major isoform. Isoform PTPB is expressed in T-cells and in placenta.
  • Sequence similarities

    Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.
    Contains 1 tyrosine-protein phosphatase domain.
  • Cellular localization

    Cytoplasm; Nucleus and Endoplasmic reticulum.
  • Information by UniProt

References

ab42575 has not yet been referenced specifically in any publications.

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