Recombinant Human Tensin 1 protein (ab159732)

Our Abpromise guarantee covers the use of ab159732 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Alternative names
- matrix-remodelling associated 6
- Matrix-remodelling-associated protein 6
- MGC88584
- MST091
- MST122
- MST127
- MSTP091
- MSTP122
- MSTP127
- MXRA6
- TENS1_HUMAN
- Tensin
- Tensin-1
- TNS
- TNS1
see all
Function

Involved in fibrillar adhesion formation. May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton.
Tissue specificity

Ubiquitous.
Sequence similarities

Contains 1 C2 tensin-type domain.
Contains 1 phosphatase tensin-type domain.
Contains 1 SH2 domain.
Post-translational
modifications

Rapidly cleaved by calpain II.
Cellular localization

Cell surface. Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Localized at cell periphery preferentially to fibrillar adhesions than focal adhesions. Translocates from the cell edge to cell center in an ITGB1BP1-dependent manner.
Target information above from: UniProt accession Q9HBL0 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

SDS-PAGE - Recombinant Human Tensin 1 protein (ab159732)

ab159732 on a 12.5% SDS-PAGE stained with Coomassie Blue.

ab159732 has not yet been referenced specifically in any publications.

Publishing research using ab159732? Please let us know so that we can cite the reference in this datasheet.

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