Recombinant Human Testin protein (ab172155)

Our Abpromise guarantee covers the use of ab172155 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Stability and Storage

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

pH: 7.2
Constituents: 0.02% DTT, 0.88% Sodium chloride, 99% PBS
Reconstitution

Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS.

Alternative names
- dkfzp586b2022
- mgc1146
- TES
- TES_HUMAN
- TESS
- tess 2
- Testin
- testin isoform 1
- Testis derived transcript (3 LIM domains)
see all
Function

Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. May act as a tumor suppressor. Inhibits tumor cell growth.
Tissue specificity

Ubiquitous.
Sequence similarities

Belongs to the prickle / espinas / testin family.
Contains 3 LIM zinc-binding domains.
Contains 1 PET domain.
Domain

The N-terminal and the C-terminal halves of the protein can asociate with each other, thereby hindering interactions with ZYX.
Cellular localization

Cytoplasm. Cell junction > focal adhesion. Detected along actin stress fibers.
Target information above from: UniProt accession Q9UGI8 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

SDS-PAGE - Recombinant Human Testin protein (ab172155)

SDS-PAGE analysis of ab172155 under Non reducing (Lane 1) or reducing conditions (Lane 2)

ab172155 has not yet been referenced specifically in any publications.

Publishing research using ab172155? Please let us know so that we can cite the reference in this datasheet.

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