Recombinant Human Testin protein (ab172155)

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Overview

  • Product name
    Recombinant Human Testin protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
      Q9UGI8-1
    • Species
      Human
    • Sequence
      MDLENKVKKMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEE HDVLLSNEEDRKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAA KKNVSINTVTYEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQL AKQLPAHDQDPSKCHELSPREVKEMEQFVKKYKSEALGVGDVKLPCEMDA QGPKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYSCYCCKLSMKEGDPAI YAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPR CAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCK PCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIG QKFMPVEGMVFCSVECKKRMS
    • Molecular weight
      48 kDa
    • Amino acids
      1 to 421
    • Tags
      His tag C-Terminus

Specifications

Our Abpromise guarantee covers the use of ab172155 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Endotoxin level
    < 0.100 Eu/µg
  • Purity
    >95% by SDS-PAGE .

  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.2
    Constituents: 0.02% DTT, 0.88% Sodium chloride, 99% PBS

  • Reconstitution
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS.

General Info

  • Alternative names
    • dkfzp586b2022
    • mgc1146
    • TES
    • TES_HUMAN
    • TESS
    • tess 2
    • Testin
    • testin isoform 1
    • Testis derived transcript (3 LIM domains)
    see all
  • Function
    Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. May act as a tumor suppressor. Inhibits tumor cell growth.
  • Tissue specificity
    Ubiquitous.
  • Sequence similarities
    Belongs to the prickle / espinas / testin family.
    Contains 3 LIM zinc-binding domains.
    Contains 1 PET domain.
  • Domain
    The N-terminal and the C-terminal halves of the protein can asociate with each other, thereby hindering interactions with ZYX.
  • Cellular localization
    Cytoplasm. Cell junction > focal adhesion. Detected along actin stress fibers.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human Testin protein (ab172155)
    SDS-PAGE - Recombinant Human Testin protein (ab172155)

    SDS-PAGE analysis of ab172155 under  Non reducing (Lane 1) or reducing conditions (Lane 2)

References

ab172155 has not yet been referenced specifically in any publications.

Publishing research using ab172155? Please let us know so that we can cite the reference in this datasheet.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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