Recombinant Human Testin protein (ab172155)

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Description

  • Product name

    Recombinant Human Testin protein
    See all Testin proteins and peptides

  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

    < 0.100 Eu/µg

  • Expression system

    Escherichia coli

  • Accession

    Q9UGI8-1

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MDLENKVKKMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEE HDVLLSNEEDRKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAA KKNVSINTVTYEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQL AKQLPAHDQDPSKCHELSPREVKEMEQFVKKYKSEALGVGDVKLPCEMDA QGPKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYSCYCCKLSMKEGDPAI YAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPR CAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCK PCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIG QKFMPVEGMVFCSVECKKRMS

    • Predicted molecular weight

      48 kDa

    • Amino acids

      1 to 421

    • Tags

      His tag C-Terminus

Specifications

Our Abpromise guarantee covers the use of ab172155 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.20
    Constituents: 0.02% DTT, 0.88% Sodium chloride, 99% PBS

  • Reconstitution
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS.

General Info

  • Alternative names

    • DKFZP586B2022
    • MGC1146
    • TES
    • TES_HUMAN
    • TESS
    • TESS 2
    • TESS2
    • Testin
    • Testis derived transcript
    • Testis derived transcript (3 LIM domains)
    see all

  • Function

    Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor. Inhibits tumor cell growth.

  • Tissue specificity

    Ubiquitous.

  • Sequence similarities

    Belongs to the prickle / espinas / testin family.
    Contains 3 LIM zinc-binding domains.
    Contains 1 PET domain.

  • Domain

    The N-terminal and the C-terminal halves of the protein can associate with each other, thereby hindering interactions with ZYX.

  • Cellular localization

    Cytoplasm. Cell junction > focal adhesion. Detected along actin stress fibers.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human Testin protein (ab172155)
    SDS-PAGE - Recombinant Human Testin protein (ab172155)

    SDS-PAGE analysis of ab172155 under  Non reducing (Lane 1) or reducing conditions (Lane 2)

References

ab172155 has not yet been referenced specifically in any publications.

Publishing research using ab172155? Please let us know so that we can cite the reference in this datasheet.

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