Recombinant Human TGF beta 2 protein (ab159690)

Submit a review Submit a question
SDS-PAGE - Recombinant Human TGF beta 2 protein (ab159690)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: ELISA, WB

    Description

    • Product name

      Recombinant Human TGF beta 2 protein
      See all TGF beta 2 proteins and peptides

    • Expression system

      Wheat germ

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        MHYCVLSAFLILHLVTVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKL TSPPEDYPEPEEVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYA KEVYKIDMPPFFPSENAIPPTFYRPYFRIVRFDVSAMEKNASNLVKAEFR VFRLQNPKARVPEQRIELYQILKSKDLTSPTQRYIDSKVVKTRAEGEWLS FDVTDAVHEWLHHKDRNLGFKISLHCPCCTFVPSNNYIIPNKSEELEARF AGIDGTSTYTSGDQKTIKSTRKKNSGKTPHLLLMLLPSYRLESQQTNRRK KRALDAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGAC PYLWSSDTQHSRVLSLYNTINPEASASPCCVSQDLEPLTILYYIGKTPKI EQLSNMIVKSCKCS

      • Predicted molecular weight

        74 kDa including tags

      • Amino acids

        1 to 414

      • Tags

        GST tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab159690 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      ELISA

      Western blot

    • Form

      Liquid

    • Additional notes

       

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    General Info

    • Alternative names

      • BSC-1 cell growth inhibitor
      • BSC1 cell growth inhibitor
      • Cetermin
      • G-TSF
      • Glioblastoma-derived T-cell suppressor factor
      • GTSF
      • LAP
      • Latency-associated peptide
      • MGC116892
      • MGF
      • Milk growth factor
      • Polyergin
      • TGF-beta-2
      • TGF-beta2
      • TGFB2
      • TGFB2_HUMAN
      • Transforming growth factor beta 2
      see all

    • Function

      TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth.

    • Involvement in disease

      A chromosomal aberration involving TGFB2 is found in a family with Peters anomaly. Translocation t(1;7)(q41;p21) with HDAC9.
      Loeys-Dietz syndrome 4
      Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD). NSAD is a frequently asymptomatic but potentially lethal disease characterized by thoracic aortic aneurysms and dissections without additional syndromic features.

    • Sequence similarities

      Belongs to the TGF-beta family.

    • Post-translational
      modifications

      The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive.

    • Cellular localization

      Secreted.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human TGF beta 2 protein (ab159690)
      SDS-PAGE - Recombinant Human TGF beta 2 protein (ab159690)
      ab159690 on a 12.5% SDS-PAGE stained with Coomassie Blue.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab159690? Please let us know so that we can cite the reference in this datasheet.

    ab159690 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    Show All Reviews Q&A
    Submit a review Submit a question

    There are currently no Customer reviews or Questions for ab159690.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com