Recombinant Human TGF beta 2 protein (ab159690)

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Description

  • Product name

    Recombinant Human TGF beta 2 protein
    See all TGF beta 2 proteins and peptides

  • Expression system

    Wheat germ

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MHYCVLSAFLILHLVTVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKL TSPPEDYPEPEEVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYA KEVYKIDMPPFFPSENAIPPTFYRPYFRIVRFDVSAMEKNASNLVKAEFR VFRLQNPKARVPEQRIELYQILKSKDLTSPTQRYIDSKVVKTRAEGEWLS FDVTDAVHEWLHHKDRNLGFKISLHCPCCTFVPSNNYIIPNKSEELEARF AGIDGTSTYTSGDQKTIKSTRKKNSGKTPHLLLMLLPSYRLESQQTNRRK KRALDAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGAC PYLWSSDTQHSRVLSLYNTINPEASASPCCVSQDLEPLTILYYIGKTPKI EQLSNMIVKSCKCS

    • Predicted molecular weight

      74 kDa including tags

    • Amino acids

      1 to 414

    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab159690 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid

  • Additional notes

     

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • BSC-1 cell growth inhibitor
    • BSC1 cell growth inhibitor
    • Cetermin
    • G-TSF
    • Glioblastoma-derived T-cell suppressor factor
    • GTSF
    • LAP
    • Latency-associated peptide
    • MGC116892
    • MGF
    • Milk growth factor
    • Polyergin
    • TGF-beta-2
    • TGF-beta2
    • TGFB2
    • TGFB2_HUMAN
    • Transforming growth factor beta 2
    see all

  • Function

    TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth.

  • Involvement in disease

    A chromosomal aberration involving TGFB2 is found in a family with Peters anomaly. Translocation t(1;7)(q41;p21) with HDAC9.
    Loeys-Dietz syndrome 4
    Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD). NSAD is a frequently asymptomatic but potentially lethal disease characterized by thoracic aortic aneurysms and dissections without additional syndromic features.

  • Sequence similarities

    Belongs to the TGF-beta family.

  • Post-translational
    modifications

    The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive.

  • Cellular localization

    Secreted.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human TGF beta 2 protein (ab159690)
    SDS-PAGE - Recombinant Human TGF beta 2 protein (ab159690)
    ab159690 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab159690 has not yet been referenced specifically in any publications.

Publishing research using ab159690? Please let us know so that we can cite the reference in this datasheet.

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