Recombinant Human TGIF2 protein (ab163717)

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Description

  • Product name

    Recombinant Human TGIF2 protein

  • Expression system

    Wheat germ

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MSDSDLGEDEGLLSLAGKRKRRGNLPKESVKILRDWLYLHRYNAYPSEQE KLSLSGQTNLSVLQICNWFINARRRLLPDMLRKDGKDPNQFTISRRGGKA SDVALPRGSSPSVLAVSVPAPTNVLSLSVCSMPLHSGQGEKPAAPFPRGE LESPKPLVTPGSTLTLLTRAEAGSPTGGLFNTPPPTPPEQDKEDFSSFQL LVEVALQRAAEMELQKQQDPSLPLLHTPIPLVSENPQ

    • Amino acids

      1 to 237

    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab163717 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid

  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.

    Previously labelled as TGF beta induced factor 2. 

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • 5' TG 3' interacting factor 2
    • 5''-TG-3''-interacting factor 2
    • Homeobox protein TGIF2
    • TGF (beta) induced transcription factor 2
    • TGF beta induced factor 2
    • TGF-beta-induced transcription factor 2
    • TGFB induced factor 2
    • TGFB-induced factor 2
    • Tgif2
    • TGIF2_HUMAN
    • Transforming growth factor beta induced factor 2
    see all

  • Function

    Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins. Probably represses transcription via the recruitment of histone deacetylase proteins.

  • Tissue specificity

    Widely expressed. Highly expressed in heart, kidney and testis. Weakly expressed in brain and prostate.

  • Sequence similarities

    Belongs to the TALE/TGIF homeobox family.
    Contains 1 homeobox DNA-binding domain.

  • Post-translational
    modifications

    The C-terminal part is phosphorylated in response to EGF signaling by the Ras/MAPK pathway.

  • Cellular localization

    Nucleus. Excluded from nucleoli.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human TGIF2 protein (ab163717)
    SDS-PAGE - Recombinant Human TGIF2 protein (ab163717)
    ab163717 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab163717 has not yet been referenced specifically in any publications.

Publishing research using ab163717? Please let us know so that we can cite the reference in this datasheet.

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