Overview

  • Product name

    Recombinant Human TIAF1 protein (denatured)
  • Protein length

    Full length protein
  • Description

    Recombinant Human TIAF1 protein

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMSS PSSPFREQSF LCAAGDAGEE SRVQVLKNEV RRGSPVLLGW VEQAYADKCV CGPSAPPAPT PPSLSQRVMC NDLFKVNPFQ LQQFRADPST ASLLLCPGGL DHKLNLRGKA WG
    • Molecular weight

      17 kDa including tags
    • Amino acids

      1 to 115
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab134518 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity

    > 85 % SDS-PAGE.

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 2.4% Urea, 0.32% Tris HCl, 10% Glycerol

General Info

  • Alternative names

    • 12 kDa TGF-beta-1-induced antiapoptotic factor
    • MAJN
    • MYO18A
    • MYSPDZ
    • SPR210
    • TGFB1 induced anti apoptotic factor 1
    • TGFB1 induced anti apoptotic factor 1 (12 kDa TGF beta1 induced antiapoptotic factor)
    • TGFB1-induced anti-apoptotic factor 1
    • TIAF1
    • TIAF1_HUMAN
    see all
  • Function

    Inhibits the cytotoxic effects of TNF-alpha and overexpressed TNF receptor adapters TRADD, FADD, and RIPK1. Involved in TGF-beta1 inhibition of IkappaB-alpha expression and suppression of TNF-mediated IkappaB-alpha degradation.
  • Tissue specificity

    Not detectable in normal kidney and liver. Up-regulated in chronic and acute allograft rejection: expressed in the inflammatory infiltrate and in tubular epithelial cells.
  • Cellular localization

    Nucleus.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab134518 (3ug)

References

ab134518 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab134518.
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