Recombinant Human TIMP1 protein (ab55236)

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SDS-PAGE - Recombinant Human TIMP1 protein (ab55236)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 95% SDS-PAGE
    • Suitable for: SDS-PAGE

    Description

    • Product name

      Recombinant Human TIMP1 protein
      See all TIMP1 proteins and peptides

    • Purity

      > 95 % SDS-PAGE.

    • Expression system

      Escherichia coli

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Amino acids

        24 to 207

    Specifications

    Our Abpromise guarantee covers the use of ab55236 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    General Info

    • Alternative names

      • Clgi
      • Collagenase inhibitor
      • Collagenase inhibitor, Human
      • EPA
      • EPO
      • Erythroid Potentiating Activity
      • Erythroid-potentiating activity
      • Fibroblast collagenase inhibitor
      • FLJ90373
      • HCI
      • Human Collagenase Inhibitor
      • Metalloproteinase inhibitor 1
      • Metalloproteinase inhibitor 1 precursor
      • OTTHUMP00000023214
      • TIMP
      • TIMP 1
      • TIMP metallopeptidase inhibitor 1
      • TIMP-1
      • Timp1
      • TIMP1 protein
      • TIMP1_HUMAN
      • Tissue Inhibitor of Metalloproteinase 1
      • Tissue inhibitor of metalloproteinases
      • Tissue inhibitor of metalloproteinases 1
      • Ttissue inhibitor of metalloproteinase 1 erythroid potentiating activity collagenase inhibitor
      see all

    • Function

      Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16. Does not act on MMP-14.

    • Sequence similarities

      Belongs to the protease inhibitor I35 (TIMP) family.
      Contains 1 NTR domain.

    • Post-translational
      modifications

      The activity of TIMP1 is dependent on the presence of disulfide bonds.

    • Cellular localization

      Secreted.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human TIMP1 protein (ab55236)
      SDS-PAGE - Recombinant Human TIMP1 protein (ab55236)
      ab55236 on SDS-PAGE

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab55236? Please let us know so that we can cite the reference in this datasheet.

    ab55236 has not yet been referenced specifically in any publications.

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