The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Cullin associated and neddylation dissociated 1
Cullin associated and neddylation dissociated protein 1
Cullin associated NEDD8 dissociated protein 1
Cullin-associated and neddylation-dissociated protein 1
Cullin-associated NEDD8-dissociated protein 1
TATA binding protein interacting protein 120A
TBP interacting protein
TBP interacting protein of 120 kDa A
TBP Interacting Protein TIP120A
TBP-interacting protein 120A
TBP-interacting protein of 120 kDa A
Enhances transcription from various types of promoters (By similarity). Regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. Prevents neddylation of CUL1 by physically blocking access to the neddylation site. Disrupts interactions between CUL1 and SKP1 and between CUL1 and F-box proteins.
Belongs to the CAND family. Contains 27 HEAT repeats.