Recombinant Human TIPE2 protein (ab164054)
- Datasheet
- References
- Protocols
Description
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Product name
Recombinant Human TIPE2 protein -
Expression system
Wheat germ -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MESFSSKSLALQAEKKLLSKMAGRSVAHLFIDETSSEVLDELYRVSKEYT HSRPQAQRVIKDLIKVAIKVAVLHRNGSFGPSELALATRFRQKLRQGAMT ALSFGEVDFTFEAAVLAGLLTECRDVLLELVEHHLTPKSHGRIRHVFDHF SDPGLLTALYGPDFTQHLGKICDGLRKLLDEGKL -
Amino acids
1 to 184 -
Tags
GST tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab164054 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
ELISA
Western blot
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Form
Liquid -
Additional notes
This product was previously labelled as Tumor necrosis factor alpha-induced protein 8-like protein 2.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- AW610835
- FLJ23467
- Inflammation factor 20
see all -
Function
Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits JUN/AP1 and NF-kappa-B activation. Promotes Fas-induced apoptosis. -
Sequence similarities
Belongs to the TNFAIP8 family. TNFAIP8L2 subfamily. -
Domain
The central region was initially thought to constitute a DED (death effector) domain. However, 3D-structure data reveal a previously uncharacterized fold that is different from the predicted fold of a DED (death effector) domain. It consists of a large, hydrophobic central cavity that is poised for cofactor binding. - Information by UniProt
Images
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SDS-PAGE - Recombinant Human TIPE2 protein (ab164054)ab164054 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Datasheets and documents
References
ab164054 has not yet been referenced specifically in any publications.
