The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Measured by its ability to inhibit TNF-beta-mediated cytotoxicity using L929 Mouse fibrosarcoma cells.
The ED50 for this effect is typically 2.5-10 µg/ml in the presence of 1 ng/ml of recombinant Human TNF-beta.
< 1.000 Eu/µg
>95% by SDS-PAGE .
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.00 Constituents: 5% Trehalose, 0.75% Glycine, 0.61% Tris
This product is an active protein and may elicit a biological response in vivo, handle with caution.
It is recommended to reconstitute the lyophilized protein in sterile deionized water to a final concentration of 400 µg/ml. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% HSA or BSA) is strongly recommended for further dilution and long term storage.
CD40 like protein precursor
Herpes virus entry mediator A
Herpesvirus entry mediator
Herpesvirus entry mediator A
Herpesvirus entry mediator ligand
Tumor necrosis factor receptor like gene2
Tumor necrosis factor receptor superfamily member 14
Tumor necrosis factor receptor superfamily member 14 precursor
Tumor necrosis factor receptor-like 2
Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.
Widely expressed, with the highest expression in lung, spleen and thymus.