Overview

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MPEVERKPKI TASRKLLLKS LMLAKAKECW EQEHEEREAE KVRYLAERIP TLQTRGLSLS ALQDLCRELH AKVEVVDEER YDIEAKCLHN TREIKDLKLK VMDLRGKFKR PPLRRVRVSA DAMLRALLGS KHKVSMDLRA NLKSVKKEDT EKERPVEVGD WRKNVEAMSG MEGRKKMFDA AKSPTSQ
    • Molecular weight

      24 kDa including tags
    • Amino acids

      1 to 187
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab136375 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity

    > 90 % SDS-PAGE.

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 2.4% Urea, 0.32% Tris HCl, 10% Glycerol

General Info

  • Alternative names

    • 2700018B22Rik
    • AI747285
    • DKFZp451O223
    • si:dz182n13.3
    • slow skeletal muscle
    • slow-twitch isoform
    • SSTNI
    • TNN1
    • Tnni1
    • TNNI1_HUMAN
    • Troponin I
    • Troponin I slow skeletal muscle
    • Troponin I slow twitch isoform
    • troponin I type 1 (skeletal, slow)
    • Troponin I, slow isoform
    see all
  • Function

    Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
  • Tissue specificity

    Highest levels observed in human skeletal muscle (e.g. gastrocnemious muscle), differentiated cultures of primary human muscle cells and rhabdomyosarcoma cells cultured in low serum medium. Expressed in C2 muscle cell myoblasts and myotubes.
  • Sequence similarities

    Belongs to the troponin I family.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab136375 (3 µg).

References

ab136375 has not yet been referenced specifically in any publications.

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