Description

  • Product name

    Recombinant Human Triadin protein
  • Expression system

    Wheat germ
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MTEITAEGNASTTTTVIDSKNGSVPKSPGKVLKRTVTEDIVTTFSSPAAW LLVIALIITWSAVAIVMFDLVDYKNFSASSIAKIGSDPLKLVRDAMEETT DWIYGFFSLLSDIISSEDEEDDDGDEDSDKGEIDEPPLRKKEIHKDKTEK QEKPERKIQTKEVGHSS
    • Amino acids

      1 to 167
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab160954 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • dJ166D18.1
    • DKFZp779I2253
    • MGC88285
    • OTTHUMP00000040354
    • TDN
    • TRDN
    • TRDN_HUMAN
    • Triadin
    • TRISK
    • TRISK 51
    • TRISK51
    see all
  • Function

    May be involved in anchoring calsequestrin to the junctional sarcoplasmic reticulum and allowing its functional coupling with the ryanodine receptor.
  • Involvement in disease

    TRDN mutations have been found in catecholaminergic polymorphic ventricular tachycardia (CPVT) (PubMed:22422768). CPVT is an arrhythmogenic disorder characterized by stress-induced, bidirectional ventricular tachycardia that may degenerate into cardiac arrest and cause sudden death.
  • Post-translational
    modifications

    Phosphorylated by CaMK2.
  • Cellular localization

    Cell membrane. Sarcoplasmic reticulum membrane.
  • Information by UniProt

Images

  • ab160954 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab160954 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab160954.
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