Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
      P09758
    • Species
      Human
    • Sequence
      HTAAQDNCTCPTNKMTVCSPDGPGGRCQCRALGSGMAVDCSTLTSKCLLL KARMSAPKNARTLVRPSEHALVDNDGLYDPDCDPEGRFKARQCNQTSVCW CVNSVGVRRTDKGDLSLRCDELVRTHHILIDLRHRPTAGAFNHSDLDAEL RRLFRERYRLHPKFVAAVHYEQPTIQIELRQNTSQKAAGDVDIGDAAYYF ERDIKGESLFQGRGGLDLRVRGEPLQVERTLIYYLDEIPPKFSMKRLTAG LIAVIVVVVVALVAGMAVLVITNRRKSGKYKKVEIKELGELRKEPSL
    • Molecular weight
      59 kDa including tags
    • Amino acids
      27 to 324

Specifications

Our Abpromise guarantee covers the use of ab114374 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 µg/µl.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Cell surface glycoprotein Trop 2
    • Cell surface glycoprotein Trop-2
    • Cell surface glycoprotein Trop2
    • Epithelial glycoprotein 1
    • GA733 1
    • GA7331
    • M1S 1
    • M1S1
    • Membrane component chromosome 1 surface marker 1
    • Pancreatic carcinoma marker protein GA733 1
    • Pancreatic carcinoma marker protein GA733-1
    • Pancreatic carcinoma marker protein GA7331
    • TACD 2
    • TACD2_HUMAN
    • TACSTD 2
    • Tacstd2
    • Trop 2
    • Trop2
    • Tumor associated calcium signal transducer 2 precursor
    • Tumor-associated calcium signal transducer 2
    see all
  • Function
    May function as a growth factor receptor.
  • Tissue specificity
    Placenta, pancreatic carcinoma cell lines.
  • Involvement in disease
    Defects in TACSTD2 are the cause of gelatinous drop-like corneal dystrophy (GDLD) [MIM:204870]; also known as lattice corneal dystrophy type III. GDLD is an autosomal recessive disorder characterized by grayish corneal amyloid deposits that cause severe visual impairment.
  • Sequence similarities
    Belongs to the EPCAM family.
    Contains 1 thyroglobulin type-1 domain.
  • Post-translational
    modifications
    The N-terminus is blocked.
  • Cellular localization
    Membrane.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human TROP2 protein (ab114374)
    SDS-PAGE - Recombinant Human TROP2 protein (ab114374)
    12.5% SDS-PAGE with ab114374 at 58.78kDa stained with Coomassie Blue.

References

ab114374 has not yet been referenced specifically in any publications.

Publishing research using ab114374? Please let us know so that we can cite the reference in this datasheet.

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