Overview

Description

  • Nature

    Recombinant
  • Source

    Baculovirus infected insect cells
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      ADPQDNCTCP TNKMTVCSPD GPGGRCQCRA LGSGMAVDCS TLTSKCLLLK ARMSAPKNAR TLVRPSEHAL VDNDGLYDPD CDPEGRFKAR QCNQTSVCWC VNSVGVRRTD KGDLSLRCDE LVRTHHILID LRHRPTAGAF NHSDLDAELR RLFRERYRLH PKFVAAVHYE QPTIQIELRQ NTSQKAAGDV DIGDAAYYFE RDIKGESLFQ GRGGLDLRVR GEPLQVERTL IYYLDEIPPK FSMKRLTHHH HHH
    • Molecular weight

      29 kDa including tags
    • Amino acids

      31 to 274
    • Tags

      His tag C-Terminus
    • Additional sequence information

      Corresponding to the extracellular domain.

Specifications

Our Abpromise guarantee covers the use of ab219424 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Endotoxin level

    < 1.000 Eu/µg
  • Purity

    > 95 % SDS-PAGE.
    Purified by using conventional chromatography techniques.
  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: PBS, 10% Glycerol

General Info

  • Alternative names

    • Cell surface glycoprotein Trop 2
    • Cell surface glycoprotein Trop-2
    • Cell surface glycoprotein Trop2
    • Epithelial glycoprotein 1
    • GA733 1
    • GA7331
    • M1S 1
    • M1S1
    • Membrane component chromosome 1 surface marker 1
    • Pancreatic carcinoma marker protein GA733 1
    • Pancreatic carcinoma marker protein GA733-1
    • Pancreatic carcinoma marker protein GA7331
    • TACD 2
    • TACD2_HUMAN
    • TACSTD 2
    • Tacstd2
    • Trop 2
    • Trop2
    • Tumor associated calcium signal transducer 2 precursor
    • Tumor-associated calcium signal transducer 2
    see all
  • Function

    May function as a growth factor receptor.
  • Tissue specificity

    Placenta, pancreatic carcinoma cell lines.
  • Involvement in disease

    Defects in TACSTD2 are the cause of gelatinous drop-like corneal dystrophy (GDLD) [MIM:204870]; also known as lattice corneal dystrophy type III. GDLD is an autosomal recessive disorder characterized by grayish corneal amyloid deposits that cause severe visual impairment.
  • Sequence similarities

    Belongs to the EPCAM family.
    Contains 1 thyroglobulin type-1 domain.
  • Post-translational
    modifications

    The N-terminus is blocked.
  • Cellular localization

    Membrane.
  • Information by UniProt

Images

  • 15% SDS-PAGE - Recombinant Human TROP2 protein (His tag) (ab219424) at 3 μg.

References

ab219424 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab219424.
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