Overview

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSHMARYEE VSVSGFEEFH RAVEQHNGKT IFAYFTGSKD AGGKSWCPDC VQAEPVVREG LKHISEGCVFIYCQVGEKPY WKDPNNDFRK NLKVTAVPTL LKYGTPQKLV ESECLQANLV EMLFSED
    • Molecular weight

      17 kDa including tags
    • Amino acids

      1 to 123
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab124598 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF
  • Purity

    > 95 % SDS-PAGE.
    ab124598 is purified using conventional chromatography techniques.
  • Form

    Liquid
  • Additional notes

    Previously labelled as TXNDC17.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 10% Glycerol, 0.29% Sodium chloride

General Info

  • Alternative names

    • 14 kDa thioredoxin-related protein
    • Protein 42-9-9
    • Thioredoxin domain-containing protein 17
    • Thioredoxin-like protein 5
    • TRP14
    • TXD17_HUMAN
    • TXNDC17
    see all
  • Function

    Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide.
  • Tissue specificity

    Ubiquitously expressed in cell lines.
  • Sequence similarities

    Belongs to the thioredoxin family.
    Contains 1 thioredoxin domain.
  • Post-translational
    modifications

    The oxidized protein is reduced by TRXR1.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt

Images

  • 15% SDS-PAGE showing ab124598 (3µg).

References

ab124598 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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