The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 µg/µl.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Short transient receptor potential channel 1
Transient receptor potential canonical 1
Transient receptor potential cation channel subfamily C member 1
Transient receptor potential channel 1
Transient receptor protein 1
TRP 1 protein
Trp related protein 1
Trpc1 transient receptor potential cation channel subfamily C member 1
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.
Seems to be ubiquitous.
Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily. Contains 4 ANK repeats.
Activation of PRKCA induces phosphorylation of TRPC1 and subsequent Ca2+ entry into cells.