Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Active: Yes
- Suitable for: Functional Studies, HPLC, SDS-PAGE
Product nameRecombinant human TSLP protein
See all TSLP proteins and peptides
Fully biologically active when compared to standard.
The ED50 as measured by its ability to induce proliferation of Human IL-7Rα and Human TSLP R co-transfected mouse BaF3 cells is less than 0.3 ng/ml.
Purity> 98 % SDS-PAGE.
> 98 % by HPLC analysis.
Endotoxin level< 1.000 Eu/µg
Expression systemEscherichia coli
Protein lengthFull length protein
SequenceMYDFTNCDFEKIKAAYLSTISKDLITYMSGTKSTEFNNTVSCSNRPHCLT EIQSLTFNPTAGCASLAKEMFAMKTKAALAIWCPGYSETQINATQAMKKR RKRKVTTNKCLEQVSQLQGLWRRFNRPLLKQQ
Predicted molecular weight15 kDa
Amino acids29 to 159
Additional sequence informationSingle non-glycosylated polypeptide chain containing 132 amino acids. This product is the mature full length protein from aa 29 to 159. The signal peptide is not included.
Our Abpromise guarantee covers the use of ab201363 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C long term. Avoid freeze / thaw cycle.
Constituents: 0.87% Sodium chloride, 99% Phosphate Buffer
Lyophilized from a 0.2µm filtered solution.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
ReconstitutionBriefly centrifuge the vial prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <-20°C. Further dilutions should be made in appropriate buffered solutions.
- Thymic stromal lymphopoietin
- Thymic stromal lymphopoietin protein TSLP
FunctionCytokine that induces the release of T cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells.
Tissue specificityExpressed in a number of tissues including heart, liver and prostate.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab201363 has been referenced in 1 publication.
- Wei Y et al. Excessive periostin expression and Th2 response in patients with nasal polyps: association with asthma. J Thorac Dis 10:6585-6597 (2018). PubMed: 30746204