Recombinant Human TTC11/FIS1 protein - BSA and Azide free (ab173037)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Tags: His tag C-Terminus
- Suitable for: SDS-PAGE, HPLC
Description
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Product name
Recombinant Human TTC11/FIS1 protein - BSA and Azide free
See all TTC11/FIS1 proteins and peptides -
Purity
> 95 % SDS-PAGE.
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. -
Endotoxin level
< 1.000 Eu/µg -
Expression system
Escherichia coli -
Accession
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Protein length
Protein fragment -
Animal free
No -
Carrier free
Yes -
Nature
Recombinant -
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Species
Human -
Sequence
MEAVLNELVSVEDLLKFEKKFQSEKAAGSVSKSTQFEYAWCLVRSKYNDD IRKGIVLLEELLPKGSKEEQRDYVFYLAVGNYRLKEYEKALKYVRGLLQT EPQNNQAKELERLIDKAMKKDGVEHHHHHH -
Predicted molecular weight
15 kDa including tags -
Amino acids
1 to 122 -
Tags
His tag C-Terminus -
Additional sequence information
Cytoplasmic domain.
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Description
Recombinant Human TTC11/FIS1 protein (BSA and azide free)
Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab173037 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
HPLC
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Form
Liquid -
Additional notes
Previously labelled as TTC11.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on Dry Ice. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituent: 0.24% Tris
Supplied as a 0.2 µM filtered solution.
General Info
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Alternative names
- 2010003O14Rik
- CGI 135
- CGI135
see all -
Function
Promotes the fragmentation of the mitochondrial network and its perinuclear clustering. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission. -
Sequence similarities
Belongs to the FIS1 family.
Contains 1 TPR repeat. -
Domain
The C-terminus is required for mitochondrial or peroxisomal localization, while the N-terminus is necessary for mitochondrial or peroxisomal fission, localization and regulation of the interaction with DNM1L. -
Post-translational
modificationsUbiquitinated by MARCH5. -
Cellular localization
Mitochondrion outer membrane. Peroxisome membrane. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab173037 has not yet been referenced specifically in any publications.