Recombinant Human TTPA protein (ab159756)
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Overview
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Product nameRecombinant Human TTPA protein
See all TTPA proteins and peptides -
Protein lengthFull length protein
Description
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NatureRecombinant
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SourceWheat germ
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Amino Acid Sequence
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SpeciesHuman
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SequenceMAEARSQPSAGPQLNALPDHSPLLQPGLAALRRRAREAGVPLAPLPLTDS FLLRFLRARDFDLDLAWRLLKNYYKWRAECPEISADLHPRSIIGLLKAGY HGVLRSRDPTGSKVLIYRIAHWDPKVFTAYDVFRVSLITSELIVQEVETQ RNGIKAIFDLEGWQFSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLINEP VIFHAVFSMIKPFLTEKIKERIHMHGNNYKQSLLQHFPDILPLEYGGEEF SMEDICQEWTNFIMKSEDYLSSISESIQ
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Amino acids1 to 278
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Tagsproprietary tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab159756 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
ELISA
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FormLiquid
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Additional notesProtein concentration is above or equal to 0.05 mg/ml.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- Alpha-tocopherol transfer protein
- Alpha-TTP
- AlphaTTP
see all -
FunctionBinds alpha-tocopherol and enhances its transfer between separate membranes.
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Involvement in diseaseDefects in TTPA are the cause of ataxia with isolated vitamin E deficiency (AVED) [MIM:277460]. AVED is an autosomal recessive disease characterized by spinocerebellar degeneration. It causes ataxia and peripheral neuropathy that resembles Friedreich ataxia. AVED patients have markedly reduced plasma levels of vitamin E.
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Sequence similaritiesContains 1 CRAL-TRIO domain.
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Cellular localizationCytoplasm.
- Information by UniProt
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Datasheets and documents
References
ab159756 has not yet been referenced specifically in any publications.