Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MAEARSQPSAGPQLNALPDHSPLLQPGLAALRRRAREAGVPLAPLPLTDS FLLRFLRARDFDLDLAWRLLKNYYKWRAECPEISADLHPRSIIGLLKAGY HGVLRSRDPTGSKVLIYRIAHWDPKVFTAYDVFRVSLITSELIVQEVETQ RNGIKAIFDLEGWQFSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLINEP VIFHAVFSMIKPFLTEKIKERIHMHGNNYKQSLLQHFPDILPLEYGGEEF SMEDICQEWTNFIMKSEDYLSSISESIQ
    • Amino acids
      1 to 278
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab159756 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Alpha-tocopherol transfer protein
    • Alpha-TTP
    • AlphaTTP
    • ATTP
    • AVED
    • Tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency)
    • TTP1
    • TTPA
    • TTPA_HUMAN
    see all
  • Function
    Binds alpha-tocopherol and enhances its transfer between separate membranes.
  • Involvement in disease
    Defects in TTPA are the cause of ataxia with isolated vitamin E deficiency (AVED) [MIM:277460]. AVED is an autosomal recessive disease characterized by spinocerebellar degeneration. It causes ataxia and peripheral neuropathy that resembles Friedreich ataxia. AVED patients have markedly reduced plasma levels of vitamin E.
  • Sequence similarities
    Contains 1 CRAL-TRIO domain.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human TTPA protein (ab159756)
    SDS-PAGE - Recombinant Human TTPA protein (ab159756)
    ab159756 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab159756 has not yet been referenced specifically in any publications.

Publishing research using ab159756? Please let us know so that we can cite the reference in this datasheet.

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