Recombinant Human TTPA protein (ab159756)
- Datasheet
- References
- Protocols
Overview
-
Product nameRecombinant Human TTPA protein
See all TTPA proteins and peptides -
Protein lengthFull length protein
Description
-
NatureRecombinant
-
SourceWheat germ
-
Amino Acid Sequence
-
SpeciesHuman
-
SequenceMAEARSQPSAGPQLNALPDHSPLLQPGLAALRRRAREAGVPLAPLPLTDS FLLRFLRARDFDLDLAWRLLKNYYKWRAECPEISADLHPRSIIGLLKAGY HGVLRSRDPTGSKVLIYRIAHWDPKVFTAYDVFRVSLITSELIVQEVETQ RNGIKAIFDLEGWQFSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLINEP VIFHAVFSMIKPFLTEKIKERIHMHGNNYKQSLLQHFPDILPLEYGGEEF SMEDICQEWTNFIMKSEDYLSSISESIQ
-
Amino acids1 to 278
-
Tagsproprietary tag N-Terminus
-
Specifications
Our Abpromise guarantee covers the use of ab159756 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
Applications
Western blot
ELISA
-
FormLiquid
-
Additional notesProtein concentration is above or equal to 0.05 mg/ml.
-
Concentration information loading...
Preparation and Storage
-
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
-
Alternative names
- Alpha-tocopherol transfer protein
- Alpha-TTP
- AlphaTTP
see all -
FunctionBinds alpha-tocopherol and enhances its transfer between separate membranes.
-
Involvement in diseaseDefects in TTPA are the cause of ataxia with isolated vitamin E deficiency (AVED) [MIM:277460]. AVED is an autosomal recessive disease characterized by spinocerebellar degeneration. It causes ataxia and peripheral neuropathy that resembles Friedreich ataxia. AVED patients have markedly reduced plasma levels of vitamin E.
-
Sequence similaritiesContains 1 CRAL-TRIO domain.
-
Cellular localizationCytoplasm.
- Information by UniProt
Images
-
SDS-PAGE - Recombinant Human TTPA protein (ab159756)ab159756 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Datasheets and documents
References
ab159756 has not yet been referenced specifically in any publications.
