Recombinant Human TWF2 protein (ab161423)
- Datasheet
- References
- Protocols
Overview
-
Product nameRecombinant Human TWF2 protein
See all TWF2 proteins and peptides -
Protein lengthFull length protein
Description
-
NatureRecombinant
-
SourceWheat germ
-
Amino Acid Sequence
-
SpeciesHuman
-
SequenceMAHQTGIHATEELKEFFAKARAGSVRLIKVVIEDEQLVLGASQEPVGRWD QDYDRAVLPLLDAQQPCYLLYRLDSQNAQGFEWLFLAWSPDNSPVRLKML YAATRATVKKEFGGGHIKDELFGTVKDDLSFAGYQKHLSSCAAPAPLTSA ERELQQIRINEVKTEISVESKHQTLQGLAFPLQPEAQRALQQLKQKMVNY IQMKLDLERETIELVHTEPTDVAQLPSRVPRDAARYHFFLYKHTHEGDPL ESVVFIYSMPGYKCSIKERMLYSSCKSRLLDSVEQDFHLEIAKKIEIGDG AELTAEFLYDEVHPKQHAFKQAFAKPKGPGGKRGHKRLIRGPGENGDDS
-
Amino acids1 to 349
-
Tagsproprietary tag N-Terminus
-
Specifications
Our Abpromise guarantee covers the use of ab161423 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
Applications
Western blot
ELISA
-
FormLiquid
-
Additional notesProtein concentration is above or equal to 0.05 mg/ml.
-
Concentration information loading...
Preparation and Storage
-
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
-
Alternative names
- A6 related protein
- A6-related protein
- A6r
see all -
FunctionActin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia.
-
Tissue specificityUbiquitously expressed (at protein level).
-
Sequence similaritiesBelongs to the actin-binding proteins ADF family. Twinfilin subfamily.
Contains 2 ADF-H domains. -
Post-translational
modificationsIn vitro, phosphorylated by PRKCZ, CK2 and SRC. -
Cellular localizationCytoplasm > cytoskeleton. Cytoplasm > perinuclear region. Cell projection > stereocilium. Perinuclear and G-actin-rich cortical actin structure sublocalization.
- Information by UniProt
Images
-
SDS-PAGE - Recombinant Human TWF2 protein (ab161423)ab161423 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Datasheets and documents
References
ab161423 has not yet been referenced specifically in any publications.
