Name: Recombinant Human TWF2 protein
SKU: ab161423

Our Abpromise guarantee covers the use of ab161423 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Alternative names
- A6 related protein
- A6-related protein
- A6r
- A6RP
- hA6RP
- MSTP011
- Protein tyrosine kinase 9 like
- Protein tyrosine kinase 9-like
- PTK 9L
- PTK9L
- PTK9L protein tyrosine kinase 9 like
- TWF 2
- Twf2
- TWF2_HUMAN
- Twinfilin 1 like protein
- Twinfilin 2
- Twinfilin actin binding protein homolog 2
- Twinfilin like protein
- Twinfilin-1-like protein
- Twinfilin-2
- Twinfilin2
see all
Function

Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia.
Tissue specificity

Ubiquitously expressed (at protein level).
Sequence similarities

Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
Contains 2 ADF-H domains.
Post-translational
modifications

In vitro, phosphorylated by PRKCZ, CK2 and SRC.
Cellular localization

Cytoplasm > cytoskeleton. Cytoplasm > perinuclear region. Cell projection > stereocilium. Perinuclear and G-actin-rich cortical actin structure sublocalization.
Target information above from: UniProt accession Q6IBS0 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

SDS-PAGE - Recombinant Human TWF2 protein (ab161423)

ab161423 on a 12.5% SDS-PAGE stained with Coomassie Blue.

ab161423 has not yet been referenced specifically in any publications.

Publishing research using ab161423? Please let us know so that we can cite the reference in this datasheet.

Recombinant Human TWF2 protein (ab161423)

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