Recombinant Human Ubiquilin/UBQLN1 protein (ab153310)

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Overview

  • Product name

    Recombinant Human Ubiquilin/UBQLN1 protein

  • Protein length

    Full length protein

Description

  • Nature

    Recombinant

  • Source

    Wheat germ
  • Amino Acid Sequence

    • Species

      Human

    • Sequence

      MAESGESGGPPGSQDSAAGAEGAGTPAAAASAEPKIMKVTVKTPKEKEEF AVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKILKDQDTLSQHGIHDGL TVHLVIKTQNRPQDHSAQQTNTAGSNVTTSSTPNSNSTSGSATSNPFGLG GLGGLAGLSSLGLNTTNFSELQSQMQRQLLSNPEMMVQIMENPFVQSMLS NHDLMRQLIMANPQMQQLIQRNPEISHMLNNPDIMRQTLELARNPAMMQE MMRNQDRALSNLESIPGGYNALRRMYTDIQEPMLSAAQEQFGGNPFASLV SNTSSGEGSQPSRTENRDPLPNPWAPQTSQSSSASSGTASTVGGTTGSTA SGTSGQSTTAPNLVPGVGASMFNTPGMQSLLQQITENPQLMQNMLSAPYM RSMMQSLSQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQNPDT LSAMSNPRAMQALLQIQQGLQTLATEAPGLIPGFTPGLGALGSTGGSSGT NGSNATPSENTSPTAGTTEPGHQQFIQQMLQALAGVNPQLQNPEVRFQQQ LEQLSAMGFLNREANLQALIATGGDINAAIERLLGSQPS

    • Amino acids

      1 to 589

    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab153310 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form

    Liquid

  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.

     This product was previously labelled as Ubiquilin

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • DA41
    • DSK2
    • FLJ90054
    • hPLIC-1
    • hPLIC1
    • PLIC-1
    • PLIC1
    • Protein linking IAP with cytoskeleton 1
    • Ubiquilin-1
    • Ubiquilin1
    • UBQL1_HUMAN
    • UBQLN1
    • UBQN
    • XDRP1
    see all

  • Function

    Links CD47 to the cytoskeleton. Promotes the surface expression of GABA-A receptors (By similarity). Promotes the accumulation of uncleaved PSEN1 and PSEN2 by stimulating their biosynthesis. Has no effect on PSEN1 and PSEN2 degradation.

  • Tissue specificity

    Ubiquitous. Highly expressed throughout the brain; detected in neurons and in neuropathological lesions, such as neurofibrillary tangles and Lewy bodies. Highly expressed in heart, placenta, pancreas, lung, liver, skeletal muscle and kidney.

  • Sequence similarities

    Contains 1 UBA domain.
    Contains 1 ubiquitin-like domain.

  • Domain

    Binds PSEN1 and PSEN2 via its UBA domain.

  • Post-translational
    modifications

    Phosphorylated.

  • Cellular localization

    Cytoplasm. Nucleus.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human Ubiquilin/UBQLN1 protein (ab153310)
    SDS-PAGE - Recombinant Human Ubiquilin/UBQLN1 protein (ab153310)
    ab153310 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab153310 has not yet been referenced specifically in any publications.

Publishing research using ab153310? Please let us know so that we can cite the reference in this datasheet.

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