Recombinant Human Ubiquilin/UBQLN1 protein (ab153310)

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SDS-PAGE - Recombinant Human Ubiquilin/UBQLN1 protein (ab153310)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: WB, ELISA

    Description

    • Product name

      Recombinant Human Ubiquilin/UBQLN1 protein

    • Expression system

      Wheat germ

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        MAESGESGGPPGSQDSAAGAEGAGTPAAAASAEPKIMKVTVKTPKEKEEF AVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKILKDQDTLSQHGIHDGL TVHLVIKTQNRPQDHSAQQTNTAGSNVTTSSTPNSNSTSGSATSNPFGLG GLGGLAGLSSLGLNTTNFSELQSQMQRQLLSNPEMMVQIMENPFVQSMLS NHDLMRQLIMANPQMQQLIQRNPEISHMLNNPDIMRQTLELARNPAMMQE MMRNQDRALSNLESIPGGYNALRRMYTDIQEPMLSAAQEQFGGNPFASLV SNTSSGEGSQPSRTENRDPLPNPWAPQTSQSSSASSGTASTVGGTTGSTA SGTSGQSTTAPNLVPGVGASMFNTPGMQSLLQQITENPQLMQNMLSAPYM RSMMQSLSQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQNPDT LSAMSNPRAMQALLQIQQGLQTLATEAPGLIPGFTPGLGALGSTGGSSGT NGSNATPSENTSPTAGTTEPGHQQFIQQMLQALAGVNPQLQNPEVRFQQQ LEQLSAMGFLNREANLQALIATGGDINAAIERLLGSQPS

      • Amino acids

        1 to 589

      • Tags

        GST tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab153310 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Western blot

      ELISA

    • Form

      Liquid

    • Additional notes

      This product was previously labelled as Ubiquilin.

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    General Info

    • Alternative names

      • DA41
      • DSK2
      • FLJ90054
      • hPLIC-1
      • hPLIC1
      • PLIC-1
      • PLIC1
      • Protein linking IAP with cytoskeleton 1
      • Ubiquilin-1
      • Ubiquilin1
      • UBQL1_HUMAN
      • UBQLN1
      • UBQN
      • XDRP1
      see all

    • Function

      Links CD47 to the cytoskeleton. Promotes the surface expression of GABA-A receptors (By similarity). Promotes the accumulation of uncleaved PSEN1 and PSEN2 by stimulating their biosynthesis. Has no effect on PSEN1 and PSEN2 degradation.

    • Tissue specificity

      Ubiquitous. Highly expressed throughout the brain; detected in neurons and in neuropathological lesions, such as neurofibrillary tangles and Lewy bodies. Highly expressed in heart, placenta, pancreas, lung, liver, skeletal muscle and kidney.

    • Sequence similarities

      Contains 1 UBA domain.
      Contains 1 ubiquitin-like domain.

    • Domain

      Binds PSEN1 and PSEN2 via its UBA domain.

    • Post-translational
      modifications

      Phosphorylated.

    • Cellular localization

      Cytoplasm. Nucleus.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human Ubiquilin/UBQLN1 protein (ab153310)
      SDS-PAGE - Recombinant Human Ubiquilin/UBQLN1 protein (ab153310)
      ab153310 on a 12.5% SDS-PAGE stained with Coomassie Blue.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab153310? Please let us know so that we can cite the reference in this datasheet.

    ab153310 has not yet been referenced specifically in any publications.

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