For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome
Recombinant Human UBXN6 protein
Full length protein
Amino Acid Sequence
MKKFFQEFKADIKFKSAGPGQKLKESVGEKAHKEKPNQPAPRPPRQGPTN EAQMAAAAALARLEQKQSRAWGPTSQDTIRNQVRKELQAEATVSGSPEAP GTNVVSEPREEGSAHLAVPGVYFTCPLTGATLRKDQRDACIKEAILLHFS TDPVAASIMKIYTFNKDQDRVKLGVDTIAKYLDNIHLHPEEEKYRKIKLQ NKVFQERINCLEGTHEFFEAIGFQKVLLPAQDQEDPEEFYVLSETTLAQP QSLERHKEQLLAAEPVRAKLDRQRRVFQPSPLASQFELPGDFFNLTAEEI KREQRLRSEAVERLSVLRTKAMREKEEQRGLRKYNYTLLRVRLPDGCLLQ GTFYARERLGAVYGFVREALQSDWLPFELLASGGQKLSEDENLALNECGL VPSALLTFSWDMAVLEDIKAAGAEPDSILKPELLSAIEKLL
1 to 441
proprietary tag N-Terminus
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.31% Glutathione, 0.79% Tris HCl
- UBX domain containing 1
- UBX domain containing 2
- UBX domain containing protein 1
Acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. MDM2 stabilization leads to MDM2-dependent TP53 degradation.
Enhanced expression in testis.
Contains 1 PUB (PUG) domain.
Contains 1 UBX domain.
The UBX domain lacks key residues critical for VCP binding.
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Localizes at the centrosome both in interphase and during mitosis.
Information by UniProt
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"