Recombinant Human Upstream Binding Protein 1 (ab159769)
- Datasheet
- References
- Protocols
Description
-
Product name
Recombinant Human Upstream Binding Protein 1 -
Expression system
Wheat germ -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
-
Species
Human -
Sequence
MAWVLKMDEVIESGLVHDFDASLSGIGQELGAGAYSMSDVLALPIFKQED SSLPLDGETEHPPFQYVMCAATSPAVKLHDETLTYLNQGQSYEIRMLDNR KMGDMPEINGKLVKSIIRVVFHDRRLQYTEHQQLEGWKWNRPGDRLLDLD IPMSVGIIDTRTNPSQLNAVEFLWDPAKRTSAFIQVHCISTEFTPRKHGG EKGVPFRIQVDAFKQNENGEYTDHLHSASCQIKVFKPKGADRKQKTDREK MEKRTAHEKEKYQPSYDTTILTEMRLEPIIEDAVEHEQKKSSKRTLPADY GDSLAKRGSCSPWPDAPTAYVNNSPSPAPTFTSPQQSTCSVPDSNSSSPN HQGDGASQTSGEQIQPSATIQETQQWLLKNRFSSYTRLFSNFSGADLLKL TKEDLVQICGAADGIRLYNSLKSRSVRPRLTIYVCREQPSSTVLQGQQQA ASSASENGSGAPYVYHAIYLEEMIASEVARKLALVFNIPLHQINQVYRQG PTGIHILVSDQMVQNFQDESCFLFSTVKAESSDGIHIILK -
Amino acids
1 to 540 -
Tags
GST tag N-Terminus
-
Specifications
Our Abpromise guarantee covers the use of ab159769 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
Applications
ELISA
Western blot
-
Form
Liquid -
Additional notes
Protein concentration is above or equal to 0.05 mg/ml. -
Concentration information loading...
Preparation and Storage
-
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
-
Alternative names
- Cp2b
- DKFZp686L1745
- LBP 1a
see all -
Function
Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box. -
Tissue specificity
Expressed in adrenal tissue, JEG-3, NCI-H295A, HepG2 and HeLa cell lines. -
Sequence similarities
Belongs to the grh/CP2 family. CP2 subfamily. -
Cellular localization
Nucleus. - Information by UniProt
Images
Datasheets and documents
References
ab159769 has not yet been referenced specifically in any publications.