Recombinant Human Upstream Binding Protein 1 (ab159769)

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Overview

  • Product name
    Recombinant Human Upstream Binding Protein 1
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MAWVLKMDEVIESGLVHDFDASLSGIGQELGAGAYSMSDVLALPIFKQED SSLPLDGETEHPPFQYVMCAATSPAVKLHDETLTYLNQGQSYEIRMLDNR KMGDMPEINGKLVKSIIRVVFHDRRLQYTEHQQLEGWKWNRPGDRLLDLD IPMSVGIIDTRTNPSQLNAVEFLWDPAKRTSAFIQVHCISTEFTPRKHGG EKGVPFRIQVDAFKQNENGEYTDHLHSASCQIKVFKPKGADRKQKTDREK MEKRTAHEKEKYQPSYDTTILTEMRLEPIIEDAVEHEQKKSSKRTLPADY GDSLAKRGSCSPWPDAPTAYVNNSPSPAPTFTSPQQSTCSVPDSNSSSPN HQGDGASQTSGEQIQPSATIQETQQWLLKNRFSSYTRLFSNFSGADLLKL TKEDLVQICGAADGIRLYNSLKSRSVRPRLTIYVCREQPSSTVLQGQQQA ASSASENGSGAPYVYHAIYLEEMIASEVARKLALVFNIPLHQINQVYRQG PTGIHILVSDQMVQNFQDESCFLFSTVKAESSDGIHIILK
    • Amino acids
      1 to 540
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab159769 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Cp2b
    • DKFZp686L1745
    • LBP 1a
    • LBP 1B
    • LBP1
    • LBP1A
    • LBP1B
    • NF2d9
    • Transcription factor LBP-1
    • UBIP1_HUMAN
    • UBP1
    • Upstream binding protein 1
    • Upstream-binding protein 1
    see all
  • Function
    Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.
  • Tissue specificity
    Expressed in adrenal tissue, JEG-3, NCI-H295A, HepG2 and HeLa cell lines.
  • Sequence similarities
    Belongs to the grh/CP2 family. CP2 subfamily.
  • Cellular localization
    Nucleus.
  • Information by UniProt

Images

  • ab159769 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab159769 has not yet been referenced specifically in any publications.

Publishing research using ab159769? Please let us know so that we can cite the reference in this datasheet.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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