Recombinant Human Upstream Binding Protein 1 (ab159769)

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Description

  • Product name

    Recombinant Human Upstream Binding Protein 1

  • Expression system

    Wheat germ

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MAWVLKMDEVIESGLVHDFDASLSGIGQELGAGAYSMSDVLALPIFKQED SSLPLDGETEHPPFQYVMCAATSPAVKLHDETLTYLNQGQSYEIRMLDNR KMGDMPEINGKLVKSIIRVVFHDRRLQYTEHQQLEGWKWNRPGDRLLDLD IPMSVGIIDTRTNPSQLNAVEFLWDPAKRTSAFIQVHCISTEFTPRKHGG EKGVPFRIQVDAFKQNENGEYTDHLHSASCQIKVFKPKGADRKQKTDREK MEKRTAHEKEKYQPSYDTTILTEMRLEPIIEDAVEHEQKKSSKRTLPADY GDSLAKRGSCSPWPDAPTAYVNNSPSPAPTFTSPQQSTCSVPDSNSSSPN HQGDGASQTSGEQIQPSATIQETQQWLLKNRFSSYTRLFSNFSGADLLKL TKEDLVQICGAADGIRLYNSLKSRSVRPRLTIYVCREQPSSTVLQGQQQA ASSASENGSGAPYVYHAIYLEEMIASEVARKLALVFNIPLHQINQVYRQG PTGIHILVSDQMVQNFQDESCFLFSTVKAESSDGIHIILK

    • Amino acids

      1 to 540

    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab159769 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid

  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • Cp2b
    • DKFZp686L1745
    • LBP 1a
    • LBP 1B
    • LBP1
    • LBP1A
    • LBP1B
    • NF2d9
    • Transcription factor LBP-1
    • UBIP1_HUMAN
    • UBP1
    • Upstream binding protein 1
    • Upstream-binding protein 1
    see all

  • Function

    Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.

  • Tissue specificity

    Expressed in adrenal tissue, JEG-3, NCI-H295A, HepG2 and HeLa cell lines.

  • Sequence similarities

    Belongs to the grh/CP2 family. CP2 subfamily.

  • Cellular localization

    Nucleus.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human Upstream Binding Protein 1 (ab159769)
    SDS-PAGE - Recombinant Human Upstream Binding Protein 1 (ab159769)
    ab159769 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab159769 has not yet been referenced specifically in any publications.

Publishing research using ab159769? Please let us know so that we can cite the reference in this datasheet.

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