Recombinant Human Upstream Binding Protein 1 (ab159769)
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- References
- Protocols
Overview
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Product nameRecombinant Human Upstream Binding Protein 1
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Protein lengthFull length protein
Description
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NatureRecombinant
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SourceWheat germ
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Amino Acid Sequence
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SpeciesHuman
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SequenceMAWVLKMDEVIESGLVHDFDASLSGIGQELGAGAYSMSDVLALPIFKQED SSLPLDGETEHPPFQYVMCAATSPAVKLHDETLTYLNQGQSYEIRMLDNR KMGDMPEINGKLVKSIIRVVFHDRRLQYTEHQQLEGWKWNRPGDRLLDLD IPMSVGIIDTRTNPSQLNAVEFLWDPAKRTSAFIQVHCISTEFTPRKHGG EKGVPFRIQVDAFKQNENGEYTDHLHSASCQIKVFKPKGADRKQKTDREK MEKRTAHEKEKYQPSYDTTILTEMRLEPIIEDAVEHEQKKSSKRTLPADY GDSLAKRGSCSPWPDAPTAYVNNSPSPAPTFTSPQQSTCSVPDSNSSSPN HQGDGASQTSGEQIQPSATIQETQQWLLKNRFSSYTRLFSNFSGADLLKL TKEDLVQICGAADGIRLYNSLKSRSVRPRLTIYVCREQPSSTVLQGQQQA ASSASENGSGAPYVYHAIYLEEMIASEVARKLALVFNIPLHQINQVYRQG PTGIHILVSDQMVQNFQDESCFLFSTVKAESSDGIHIILK
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Amino acids1 to 540
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TagsGST tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab159769 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
ELISA
Western blot
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FormLiquid
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Additional notesProtein concentration is above or equal to 0.05 mg/ml.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- Cp2b
- DKFZp686L1745
- LBP 1a
see all -
FunctionFunctions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.
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Tissue specificityExpressed in adrenal tissue, JEG-3, NCI-H295A, HepG2 and HeLa cell lines.
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Sequence similaritiesBelongs to the grh/CP2 family. CP2 subfamily.
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Cellular localizationNucleus.
- Information by UniProt
Images
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SDS-PAGE - Recombinant Human Upstream Binding Protein 1 (ab159769)ab159769 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Datasheets and documents
References
ab159769 has not yet been referenced specifically in any publications.
