Recombinant Human Urokinase protein (ab92767)

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SDS-PAGE - Recombinant Human Urokinase protein (ab92767)

    Key features and details

    • Expression system: Insect cells
    • Suitable for: SDS-PAGE, Functional Studies

    Description

    • Product name

      Recombinant Human Urokinase protein
      See all Urokinase proteins and peptides

    • Biological activity

      ab92767 is fully complexable with Human PAI-1.

    • Expression system

      Insect cells

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

    Specifications

    Our Abpromise guarantee covers the use of ab92767 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      Functional Studies

    • Form

      Liquid

    • Additional notes

      Solubility: > 2 mg/mL ab92767 is fully complexable with Human PAI-1.
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 5.00
      Constituents: 0.41% Sodium acetate, 0.0292% EDTA, 0.58% Sodium chloride

    General Info

    • Alternative names

      • ATF
      • ATF uPA
      • BDPLT5
      • Plasminogen activator
      • Plasminogen activator urinary
      • Plasminogen activator urokinase
      • PLAU
      • QPD
      • u PA
      • U plasminogen activator
      • u-PA
      • U-plasminogen activator
      • uPA
      • URK
      • UROK_HUMAN
      • Urokinase plasminogen activator
      • Urokinase type plasminogen activator
      • Urokinase type plasminogen activator precursor
      • Urokinase-type plasminogen activator chain B
      see all

    • Function

      Specifically cleave the zymogen plasminogen to form the active enzyme plasmin.

    • Tissue specificity

      Expressed in the prostate gland and prostate cancers.

    • Sequence similarities

      Belongs to the peptidase S1 family.
      Contains 1 EGF-like domain.
      Contains 1 kringle domain.
      Contains 1 peptidase S1 domain.

    • Post-translational
      modifications

      Phosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding.

    • Cellular localization

      Secreted.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human Urokinase protein (ab92767)
      SDS-PAGE - Recombinant Human Urokinase protein (ab92767)
      10% SDS-PAGE analysis of ab92767:
      Lane 1. 3ug ab92767 non reduced
      Lane 2. 3ug ab92767 + 12ug PAI-1 non reduced
      Lane 3. Prestained standard

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab92767? Please let us know so that we can cite the reference in this datasheet.

    ab92767 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Submit a question

    Question

    What is the amino acid sequence of the HMW urokinase ab92767?

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    Answer

    The urokinase protein ab92767 is amino acids 21 – 431. The numbering refers to to the UniProt record P00749. Here is a link to the page. http://www.uniprot.org/uniprot/P00749

    And here is the amino acid sequence.

    SNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQHCEIDKSKTCYEGNGHFYRG

    KASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRRRPWCYVQVGLK

    PLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKIIGGEFTTIENQPWFAAIYRRH

    RGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLI

    LHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITGFGK

    ENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPL

    VCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTKEENGLAL

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