The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Deubiquitinating enzyme 21
deubiquitinating enzyme 23
Ubiquitin carboxyl terminal hydrolase 21
ubiquitin carboxyl terminal hydrolase 23
Ubiquitin carboxyl-terminal hydrolase 21
ubiquitin specific peptidase 21
Ubiquitin specific processing protease 21
ubiquitin specific protease 16
ubiquitin specific protease 21
ubiquitin specific protease 23
Ubiquitin thioesterase 21
Ubiquitin thiolesterase 21
ubiquitin thiolesterase 23
ubiquitin-specific protease 23, formerly
Ubiquitin-specific-processing protease 21
Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination (By similarity). Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates.
Highly expressed in heart, pancreas and skeletal muscle. Also expressed in brain, placenta, liver and kidney, and at very low level in lung.
Belongs to the peptidase C19 family. USP21 subfamily.