Recombinant Human USP46 protein (ab177681)

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Description

  • Product name

    Recombinant Human USP46 protein

  • Purity

    > 90 % SDS-PAGE.
    ab177681 is purified using conventional chromatography techniques.

  • Expression system

    Escherichia coli

  • Accession

    P62068

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSMTVRNIA SICNMGTNAS ALEKDIGPEQ FPINEHYFGL VNFGNTCYCN SVLQALYFCR PFRENVLAYK AQQKKKENLL TCLADLFHSI ATQKKKVGVI PPKKFISRLR KENDLFDNYM QQDAHEFLNY LLNTIADILQ EEKKQEKQNG KLKNGNMNEP AENNKPELTW VHEIFQGTLT NETRCLNCET VSSKDEDFLD LSVDVEQNTS ITHCLRDFSN TETLCSEQKY YCETCCSKQE AQKRMRVKKL PMILALHLKR FKYMEQLHRY TKLSYRVVFP LELRLFNTSS DAVNLDRMYD LVAVVVHCGS GPNRGHYITI VKSHGFWLLF DDDIVEKIDA QAIEEFYGLT SDISKNSESG YILFYQSRE

    • Predicted molecular weight

      45 kDa including tags

    • Amino acids

      1 to 366

    • Tags

      His tag N-Terminus

    • Additional sequence information

      NP_073743

Specifications

Our Abpromise guarantee covers the use of ab177681 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.88% Sodium chloride, 10% Glycerol, 0.02% DTT

General Info

  • Alternative names

    • Deubiquitinating enzyme 46
    • FLJ11850
    • FLJ12552
    • FLJ14283
    • FLJ39393
    • Ubiquitin carboxyl terminal hydrolase 46
    • Ubiquitin carboxyl-terminal hydrolase 46
    • Ubiquitin specific peptidase 46
    • Ubiquitin specific processing protease 46
    • Ubiquitin specific protease 46
    • Ubiquitin thioesterase 46
    • Ubiquitin thiolesterase 46
    • Ubiquitin-specific-processing protease 46
    • UBP46_HUMAN
    • USP46
    see all

  • Function

    Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.

  • Tissue specificity

    Broadly expressed.

  • Sequence similarities

    Belongs to the peptidase C19 family. USP12/USP46 subfamily.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human USP46 protein (ab177681)
    SDS-PAGE - Recombinant Human USP46 protein (ab177681)

    15% SDS-PAGE analysis of 3µg ab177681.

References

ab177681 has not yet been referenced specifically in any publications.

Publishing research using ab177681? Please let us know so that we can cite the reference in this datasheet.

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