Recombinant Human USP46 protein (ab177681)

Submit a review Submit a question
SDS-PAGE - Recombinant Human USP46 protein (ab177681)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 90% SDS-PAGE
    • Tags: His tag N-Terminus
    • Suitable for: SDS-PAGE, MS

    Description

    • Product name

      Recombinant Human USP46 protein
      See all USP46 proteins and peptides

    • Purity

      > 90 % SDS-PAGE.
      ab177681 is purified using conventional chromatography techniques.

    • Expression system

      Escherichia coli

    • Accession

      P62068

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        MGSSHHHHHH SSGLVPRGSH MGSMTVRNIA SICNMGTNAS ALEKDIGPEQ FPINEHYFGL VNFGNTCYCN SVLQALYFCR PFRENVLAYK AQQKKKENLL TCLADLFHSI ATQKKKVGVI PPKKFISRLR KENDLFDNYM QQDAHEFLNY LLNTIADILQ EEKKQEKQNG KLKNGNMNEP AENNKPELTW VHEIFQGTLT NETRCLNCET VSSKDEDFLD LSVDVEQNTS ITHCLRDFSN TETLCSEQKY YCETCCSKQE AQKRMRVKKL PMILALHLKR FKYMEQLHRY TKLSYRVVFP LELRLFNTSS DAVNLDRMYD LVAVVVHCGS GPNRGHYITI VKSHGFWLLF DDDIVEKIDA QAIEEFYGLT SDISKNSESG YILFYQSRE

      • Predicted molecular weight

        45 kDa including tags

      • Amino acids

        1 to 366

      • Tags

        His tag N-Terminus

      • Additional sequence information

        NP_073743

    Specifications

    Our Abpromise guarantee covers the use of ab177681 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      Mass Spectrometry

    • Mass spectrometry

      MALDI-TOF

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 8.00
      Constituents: 0.32% Tris HCl, 0.88% Sodium chloride, 10% Glycerol (glycerin, glycerine), 0.02% DTT

    General Info

    • Alternative names

      • Deubiquitinating enzyme 46
      • FLJ11850
      • FLJ12552
      • FLJ14283
      • FLJ39393
      • Ubiquitin carboxyl terminal hydrolase 46
      • Ubiquitin carboxyl-terminal hydrolase 46
      • Ubiquitin specific peptidase 46
      • Ubiquitin specific processing protease 46
      • Ubiquitin specific protease 46
      • Ubiquitin thioesterase 46
      • Ubiquitin thiolesterase 46
      • Ubiquitin-specific-processing protease 46
      • UBP46_HUMAN
      • USP46
      see all

    • Function

      Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.

    • Tissue specificity

      Broadly expressed.

    • Sequence similarities

      Belongs to the peptidase C19 family. USP12/USP46 subfamily.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human USP46 protein (ab177681)
      SDS-PAGE - Recombinant Human USP46 protein (ab177681)

      15% SDS-PAGE analysis of 3µg ab177681.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab177681? Please let us know so that we can cite the reference in this datasheet.

    ab177681 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    Show All Reviews Q&A
    Submit a review Submit a question

    There are currently no Customer reviews or Questions for ab177681.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com