The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
>90% by SDS-PAGE. ab169916 was expressed in E.coli as inclusion bodies then refolded using “temperature shift inclusion body refolding” technology and chromatographically purified.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituent: 0.32% Tris HCl Note: Buffer contains NaCl, KCl, EDTA, arginine, DTT and Glycerol.
Vascular Cell Adhesion Molecule 1
Vascular cell adhesion protein 1
Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue.