Recombinant human VEGF Receptor 1 protein (ab84771)
Key features and details
- Expression system: Insect cells
- Purity: > 80% Densitometry
- Active: Yes
- Suitable for: WB, Functional Studies, SDS-PAGE
Description
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Product name
Recombinant human VEGF Receptor 1 protein
See all VEGF Receptor 1 proteins and peptides -
Biological activity
The Specific activity of ab84771 was determined to be 35 nmol/min/mg.
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Purity
> 80 % Densitometry.
Affinity purified. -
Expression system
Insect cells -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Amino acids
784 to 1338
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Associated products
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Substrate reagent
Specifications
Our Abpromise guarantee covers the use of ab84771 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
Functional Studies
SDS-PAGE
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Form
Liquid -
Additional notes
ab204862 (IRS1 peptide) can be utilized as a substrate for assessing kinase activity
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.50
Constituents: 0.0038% EGTA, 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol (glycerin, glycerine), 0.87% Sodium chlorideThis product is an active protein and may elicit a biological response in vivo, handle with caution.
General Info
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Alternative names
- EC 2.7.10.1
- FLT
- FLT 1
see all -
Function
Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis. -
Tissue specificity
Mostly in normal lung, but also in placenta, liver, kidney, heart and brain tissues. Specifically expressed in most of the vascular endothelial cells, and also expressed in peripheral blood monocytes. Isoform sFlt1 is strongly expressed in placenta. -
Sequence similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Contains 7 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain. -
Cellular localization
Secreted and Cell membrane. - Information by UniProt
Images
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Functional Studies - Recombinant human VEGF Receptor 1 protein (ab84771)The specific activity of VEGF Receptor 1 (ab84771) was determined to be 41 nmol/min/mg as per activity assay protocol
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SDS-PAGE - Recombinant human VEGF Receptor 1 protein (ab84771)SDS PAGE analysis of ab84771 -
SDS-PAGE - Recombinant human VEGF Receptor 1 protein (ab84771)SDS PAGE analysis of ab84771 -
Functional Studies - Recombinant human VEGF Receptor 1 protein (ab84771)The Specific activity of ab84771 was determined to be 35 nmol/min/mg. -
SDS-PAGE - Recombinant human VEGF Receptor 1 protein (ab84771)SDS-PAGE showing ab84771 at approximately 94kDa.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab84771 has not yet been referenced specifically in any publications.