Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
      Q9UBQ0
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MGSHMMLVLV LGDLHIPHRC NSLPAKFKKL LVPGKIQHIL CTGNLCTKES YDYLKTLAGD VHIVRGDFDE NLNYPEQKVV TVGQFKIGLI HGHQVIPWGD MASLALLQRQ FDVDILISGH THKFEAFEHE NKFYINPGSA TGAYNALETN IIPSFVLMDI QASTVVTYVY QLIGDDVKVE RIEYKKP
    • Molecular weight
      23 kDa including tags
    • Amino acids
      1 to 182
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab124582 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 90 % SDS-PAGE.
    ab124582 is purified using conventional chromatography techniques.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 40% Glycerol, 0.88% Sodium chloride

General Info

  • Alternative names
    • DC15
    • DC7
    • DKFZp564F0223
    • FLJ20492
    • hVPS29
    • PEP11
    • PEP11 homolog
    • Retromer protein
    • Vacuolar protein sorting 29
    • Vacuolar protein sorting 29 (yeast homolog)
    • Vacuolar protein sorting 29 (yeast)
    • Vacuolar protein sorting 29 homolog
    • Vacuolar protein sorting 29 homolog (S. cerevisiae)
    • Vacuolar protein sorting associated protein 29
    • Vacuolar protein sorting-associated protein 29
    • Vacuolar sorting protein VPS29/PEP11
    • Vesicle protein sorting 29
    • VPS 29
    • VPS29
    • VPS29 retromer complex component
    • VPS29_HUMAN
    • x 007 protein
    see all
  • Function
    Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro).
  • Tissue specificity
    Ubiquitous. Highly expressed in heart, lung, placenta, spleen, peripheral blood leukocytes, thymus, colon skeletal muscle, kidney and brain.
  • Sequence similarities
    Belongs to the VPS29 family.
  • Cellular localization
    Cytoplasm. Membrane. Endosome membrane.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human VPS29 protein (ab124582)
    SDS-PAGE - Recombinant Human VPS29 protein (ab124582)
    15% SDS-PAGE showing ab124582 at approximately 23.2kDa (3µg).

References

ab124582 has not yet been referenced specifically in any publications.

Publishing research using ab124582? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

Submit a review Submit a question

There are currently no Customer reviews or Questions for ab124582.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up