Recombinant Human VPS29 protein (ab124582)

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Overview

  • Product name

    Recombinant Human VPS29 protein

  • Protein length

    Full length protein

Description

  • Nature

    Recombinant

  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
      Q9UBQ0

    • Species

      Human

    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSHMMLVLV LGDLHIPHRC NSLPAKFKKL LVPGKIQHIL CTGNLCTKES YDYLKTLAGD VHIVRGDFDE NLNYPEQKVV TVGQFKIGLI HGHQVIPWGD MASLALLQRQ FDVDILISGH THKFEAFEHE NKFYINPGSA TGAYNALETN IIPSFVLMDI QASTVVTYVY QLIGDDVKVE RIEYKKP

    • Molecular weight

      23 kDa including tags

    • Amino acids

      1 to 182

    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab124582 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF

  • Purity

    > 90 % SDS-PAGE.
    ab124582 is purified using conventional chromatography techniques.

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 40% Glycerol, 0.88% Sodium chloride

General Info

  • Alternative names

    • DC15
    • DC7
    • DKFZp564F0223
    • FLJ20492
    • hVPS29
    • PEP11
    • PEP11 homolog
    • Retromer protein
    • Vacuolar protein sorting 29
    • Vacuolar protein sorting 29 (yeast homolog)
    • Vacuolar protein sorting 29 (yeast)
    • Vacuolar protein sorting 29 homolog
    • Vacuolar protein sorting 29 homolog (S. cerevisiae)
    • Vacuolar protein sorting associated protein 29
    • Vacuolar protein sorting-associated protein 29
    • Vacuolar sorting protein VPS29/PEP11
    • Vesicle protein sorting 29
    • VPS 29
    • VPS29
    • VPS29 retromer complex component
    • VPS29_HUMAN
    • x 007 protein
    see all

  • Function

    Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro).

  • Tissue specificity

    Ubiquitous. Highly expressed in heart, lung, placenta, spleen, peripheral blood leukocytes, thymus, colon skeletal muscle, kidney and brain.

  • Sequence similarities

    Belongs to the VPS29 family.

  • Cellular localization

    Cytoplasm. Membrane. Endosome membrane.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human VPS29 protein (ab124582)
    SDS-PAGE - Recombinant Human VPS29 protein (ab124582)
    15% SDS-PAGE showing ab124582 at approximately 23.2kDa (3µg).

References

ab124582 has not yet been referenced specifically in any publications.

Publishing research using ab124582? Please let us know so that we can cite the reference in this datasheet.

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