Overview

Description

  • Nature

    Recombinant
  • Source

    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Molecular weight

      128 kDa including tags
    • Amino acids

      1 to 887

Associated products

Specifications

Our Abpromise guarantee covers the use of ab125629 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity

    The specific activity of PI 3 Kinase Class 3 was determined to be 98 nmol /min/mg.
  • Applications

    Western blot

    Functional Studies

    SDS-PAGE

  • Form

    Liquid
  • Additional notes

     This product was previously labelled as PI 3 Kinase Class 3

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol, 0.88% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names

    • hVps34
    • MGC61518
    • Phosphatidylinositol 3 kinase catalytic subunit type 3
    • Phosphatidylinositol 3 kinase class 3
    • Phosphatidylinositol 3 kinase p100 subunit
    • Phosphatidylinositol 3-kinase catalytic subunit type 3
    • Phosphatidylinositol 3-kinase p100 subunit
    • Phosphoinositide 3 kinase class 3
    • Phosphoinositide-3-kinase class 3
    • PI3 kinase type 3
    • PI3-kinase type 3
    • PI3K type 3
    • Pik3c3
    • PK3C3_HUMAN
    • PtdIns 3 kinase type 3
    • PtdIns-3-kinase type 3
    • Vps 34
    • Vps34
    see all
  • Function

    Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis.
  • Tissue specificity

    Ubiquitously expressed, with a highest expression in skeletal muscle.
  • Sequence similarities

    Belongs to the PI3/PI4-kinase family.
    Contains 1 PI3K/PI4K domain.
  • Cellular localization

    Midbody.
  • Information by UniProt

Images

  • SDS-PAGE of Human VPS34 protein.

  • The specific activity of ab125629 was determined to be 98 nmol/min/mg.

References

ab125629 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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