Overview

Description

  • Nature

    Recombinant
  • Source

    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MPTTQQSPQDEQEKLLDEAIQAVKVQSFQMKRCLDKNKLMDALKHASNML GELRTSMLSPKSYYELYMAISDELHYLEVYLTDEFAKGRKVADLYELVQY AGNIIPRLYLLITVGVVYVKSFPQSRKDILKDLVEMCRGVQHPLRGLFLR NYLLQCTRNILPDEGEPTDEETTGDISDSMDFVLLNFAEMNKLWVRMQHQ GHSRDREKRERERQELRILVGTNLVRLSQLEGVNVERYKQIVLTGILEQV VNCRDALAQEYLMECIIQVFPDEFHLQTLNPFLRACAELHQNVNVKNIII ALIDRLALFAHREDGPGIPADIKLFDIFSQQVATVIQSRQDMPSEDVVSL QVSLINLAMKCYPDRVDYVDKVLETTVEIFNKLNLEHIATSSAVSKELTR LLKIPVDTYNNILTVLKLKHFHPLFEYFDYESRKSMSCYVLSNVLDYNTE IVSQDQVDSIMNLVSTLIQDQPDQPVEDPDPEDFADEQSLVGRFIHLLRS EDPDQQYLILNTARKHFGAGGNQRIRFTLPPLVFAAYQLAFRYKENSKVD DKWEKKCQKIFSFAHQTISALIKAELAELPLRLFLQGALAAGEIGFENHE TVAYEFMSQAFSLYEDEISDSKAQLAAITLIIGTFERMKCFSEENHEPLR TQCALAASKLLKKPDQGRAVSTCAHLFWSGRNTDKNGEELHGGKRVMECL KKALKIANQCMDPSLQVQLFIEILNRYIYFYEKENDAVTIQVLNQLIQKI REDLPNLESSEETEQINKHFHNTLEHLRLRRESPESEGPIYEGLIL
    • Molecular weight

      118 kDa including tags
    • Amino acids

      1 to 796

Specifications

Our Abpromise guarantee covers the use of ab132953 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

    ELISA

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 µg/µl.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • DKFZp434E1211
    • DKFZp434P1672
    • FLJ10752
    • FLJ13588
    • FLJ20388
    • hVPS35
    • Maternal embryonic 3
    • Maternal-embryonic 3
    • MEM 3
    • MEM3
    • PARK17
    • TCCCTA00141
    • Vacuolar protein sorting 35
    • Vacuolar protein sorting 35 (yeast)
    • Vacuolar protein sorting 35 homolog
    • Vacuolar protein sorting associated protein 35
    • Vacuolar protein sorting-associated protein 35
    • Vesicle protein sorting 35
    • VPS 35
    • VPS35
    • VPS35_HUMAN
    see all
  • Function

    Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA).
  • Tissue specificity

    Ubiquitous. Highly expressed in heart, brain, placenta, skeletal muscle, spleen, thymus, testis, ovary, small intestine, kidney and colon.
  • Sequence similarities

    Belongs to the VPS35 family.
  • Cellular localization

    Cytoplasm. Membrane.
  • Information by UniProt

Images

  • 12.5% SDS-PAGE analysis of ab132953 stained with Coomassie Blue.

References

ab132953 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab132953.
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