The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
DNA repair protein XRCC2
X ray repair complementing defective repair in Chinese hamster cells 2
X ray repair cross complementing protein 2
X-ray repair cross-complementing protein 2
Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
Belongs to the RecA family. RAD51 subfamily.
Phosphorylated upon DNA damage, probably by ATM or ATR.